Sentinel lymph node is the first regional lymph node that drains the lymph from the primary tumor. It is potentially the first node to receive the seeding of lymph-borne metastatic cells. This study aimed to discuss lymphoscintigraphy procedural guidelines for detection of sentinel node using (99m)Tc-Phytate in Isfahan, Iran. Moreover, the preliminary results of the first year's clinical experi...

OBJECTIVES To determine the sensitivity, accuracy, and clinical relevance of intra-operative examination of sentinel lymph nodes in breast cancer management. DESIGN Retrospective study. SETTING Private anatomical pathology practice. PARTICIPANTS Three hundred breast cancer patients who underwent axillary sentinel lymph node biopsies for intra-operative assessment between January 2004 and ...

PURPOSE Subsequent to the American College of Surgeons Oncology Group (ACOSOG) Z0011 and After Mapping of the Axilla: Radiotherapy or Surgery (AMAROS) trials, complete axillary lymph node dissection is not routinely performed, even in cases where metastatic sentinel lymph nodes are detected. We investigated the percentage of N2 or N3 stages in T1-2 invasive breast cancer patients with no lympha...

PURPOSE To evaluate and present our initial results of a new marker (hemosiderin) for mammary sentinel lymph node identification in an experimental model. METHODS Skins mapped like a lymphatic duct draining to the axilla in patients submitted to breast biopsy, in our mastology service, stimulated us to try it in an animal model (female dogs). Our theory was that some blood derivate (hemosider...

HYPOTHESIS The incidence of sentinel node (SN) metastases from invasive breast cancer might be affected by the technique used to obtain biopsy specimens from the primary tumor before sentinel lymph node dissection. DESIGN Prospective database study. SETTING The John Wayne Cancer Institute. PATIENTS AND METHODS We identified 663 patients with biopsy-proven invasive breast cancer who underw...

378 www.thelancet.com/oncology Vol 15 April 2014 tumour is malignant melanoma. Likewise, sentinel lymphadenectomy is not useful for staging disease in the management of atypical Spitz tumours because metastases from these tumours are not prognostic. The results of Lallas and colleagues’ study establish that sentinel lymph node metastasis is not of diagnostic or prognostic signifi cance in patie...

................................................................................................................................... 1 LIST OF ABBREVIATIONS ......................................................................................................... 4 BACKGROUND AND INTRODUCTION ................................................................................... 5 The ‘black cancer’:...