Background: Oxidative modification of low-density lipoprotein (LDL) appears to be an early step in the pathogenesis of atherosclerosis. Meanwhile, myeloperoxidase (MPO)-catalyzed reaction is one of the potent pathway for LDL oxidation in vivo. The aim of this study was to evaluate in vitro antioxidant effects of vitamins C and E on LDL oxidation mediated by MPO. Methods: MPO was isolated from f...

Human milk was subjected to heat treatments of graded severity and examined for its content of immunoglobulins, lactoferrin, lysozyme, vitamin B12-and folate-binder proteins, and lactoperoxidase. Holder pasteurization (62.5degrees C 30 minutes) reduced the IgA titer by 20%, and destroyed the small content of IgM and most of the lactoferrin. Lysozyme was stable to this treatment, but with an inc...

Background: The role of oxidative stress in endosulfan-induced reproductive toxicity has been implicated. This study was performed to evaluate the possible protective effect of vitamins E and C, against endosulfan-induced reproductive toxicity in rats. Methods: Fifty adult male Sprague–Dawley rats were randomly divided into five groups (n=10 each). The groups included a control receivin...

background: paraquat is nonselective bipyridyl herbicide that induces hepatotoxicity through oxidative stress. vitamin c and chitosan have antioxidant as well as radical scavenger properties and show protective effects against reactive oxygen species (ros). in the present study, hepatoprotective effects of chitosan and vitamin c were evaluated in common carp exposed to paraquat. methods: while ...