BACKGROUND Septal perforation is an uncommon but very bothersome illness and treatment is difficult particularly with large perforations. We wanted to establish the etiology and size of nasal septal perforations in an attempt to implement preventive measures. METHODS This is an open, prospective clinical study of patients seen at our hospital from 1981 to 2005. The clinical data of size, gend...

OBJECTIVE To examine the incidence of raised pulmonary artery pressure and resistance in adults with isolated atrial septal defect within the oval fossa (so called secundum defect) or sinus venosus defect. DESIGN A historical, retrospective, unrandomised study. SETTING A tertiary referral centre. METHODS Cardiac catheterisation was performed in all patients, with measurement of pulmonary ...

Echocardiographic studies of interventricular septal motion were performed in 26 consecutive patients with the Wolff-Parkinson-White (WPW) syndrome and in ten normal subjects. All patients with types A or B pre-excitation were subclassified into groups I to IV on the basis of their electrocardiogram utilizing the method of Boineau and associates. In all 14 patients with type A (Group III or IV)...

INTRODUCTION The Amplatzer septal occluder is frequently used for percutaneous closure of an atrial septal defect. Complications include thrombosis and embolism, dislocation, cardiac perforation, and, rarely, infection. We report the case of a patient who had survived an occluder-related thromboembolism two years previously. CASE PRESENTATION A 72-year-old Caucasian woman had received a septa...

A combined septal perforation repair and rhinoplasty was performed in 80 patients presenting with septal perforations (size 1 to 5 cm) and external nasal deformities. The external rhinoplasty approach was used for all cases and the perforation was repaired using bilateral intranasal mucosal advancement flaps with a connective tissue interposition graft in between. Complete closure of the perfor...

We read with interest the article by Maron et al.1 We would like to commend them for utilizing the term, “hypertrophic cardiomyopathy,” in this report, instead of the term, “asymmetric septal hypertrophy,” which has now proven rather nonspecific. We were also pleased to note that Maron et al1 now recognize that asymmetric septal hypertrophy is not pathognomonic of hypertrophic cardiomyopathy. N...

Postoperative performance in acquisition and reversal learning of septal rats was investigated and compared with control rats in three experiments. Experiment I involved a simultaneous black-white discrimination task. The number of errors in normal and septal rats was similar in acquisition and reversal learning. Both septal and normal rats manifested directional response sets. Experiment II ex...

At present, surgical septal myectomy is regarded as the "gold standard" treatment for most patients with obstructive hypertrophic cardiomyopathy (HCM) and drug-refractory symptoms. However, the best results are obtained by those surgeons who have extensive experience with this operation at a small number of referral centers. In the mid-1990s, percutaneous alcohol septal ablation was introduced ...

We performed simultaneous echocardiographic and hemodynamic studies in 11 patients with muscular subaortic stenosis to determine whether systolic anterior motion (SAM) of the anterior mitral leaflet and the pressure gradient are related quantitatively. SAM without septal contact was associated with either no gradient or a small impulse gradient of less than 10 mm Hg. SAM with septal contact was...

OBJECTIVES Patients with hypertrophic obstructive cardiomyopathy and basal septal thickness <18 mm are often considered unsuitable candidates for myectomy. Mitral valve (MV) replacement is frequently performed instead. We aimed to determine whether septal thickness affects outcomes and adequacy of myectomy. METHODS Clinical and echocardiographic data were reviewed for 1486 consecutive adult p...