We prospectively evaluated the efficacy and toxicity of intravenously administered colistin in 35 episodes of ventilator-associated pneumonia (VAP) due to multidrug-resistant Acinetobacter baumannii. Microbiological diagnosis was performed with use of quantitative culture. In 21 patients, the episodes were caused by a strain susceptible exclusively to colistin (the CO group) and were all treate...

BACKGROUND No single anticoagulant has been proven effective for sepsis-associated disseminated intravascular coagulation (DIC). Thus, the concomitant use of antithrombin concentrate and recombinant thrombomodulin has been conceived. This observational study was conducted to investigate the efficacy and safety of this combination therapy. METHODS A total of 510 septic DIC patients who receive...

Background. The sequential organ failure assessment (SOFA) score has been recommended to triage critically ill patients in the intensive care unit (ICU). This study aimed to compare the performance of our proposed MSOFA and original SOFA scores in predicting ICU mortality. Methods. This prospective observational study was conducted on 250 patients admitted to the ICU. Both tools scores were cal...

BACKGROUND/AIM The aim of this study was to determine mortality rates and to evaluate clinical features of patients with active tuberculosis (TB) requiring intensive care unit (ICU) admission. MATERIALS AND METHODS The medical records of active TB patients requiring ICU admission were retrospectively reviewed over a 5-year period. RESULTS Sixteen patients with active TB admitted to the ICU ...

PURPOSE Extracorporeal membrane oxygenation (ECMO) has been utilized for critically ill patients, such as those with life-threatening respiratory failure or post-cardiotomy cardiogenic shock. This study compares the predictive value of Acute Physiology, Age, and Chronic Health Evaluation II (APACHE II), Sequential Organ Failure Assessment (SOFA), and Organ System Failure (OSF) obtained on the f...

OBJECTIVES Poor survival of patients with a haematological malignancy admitted to the intensive care unit (ICU) prompts for proper admission triage and prediction of ICU treatment failure and long-term mortality. We therefore tried to find predictors of the latter outcomes. METHODS A retrospective analysis of charts and a prospective follow-up study were done, of haemato-oncological patients,...

retrospective cohort study to examine, among other things, the prognostic value of the Sequential Organ Failure Assessment (SOFA) score for predicting 90-day mortality in critically ill cirrhotic patients receiving liver transplantation. Th ey conclude that the SOFA score at admission, at 48 hours and at liver transplantation was not independently associated with the outcome. Th is association ...

Background: Direct hemoperfusion with a polymyxin B (PMX) often produces improvement in patients with sepsis caused by bacteria other than those classified as gramnegative. The aim of the present study is to clarify the therapeutic effects of PMX in patients with sepsis caused by bacteria other than gram-negative bacteria. Methods and Findings: We enrolled 41 patients with severe sepsis includi...

BACKGROUND prognostic scores have been validated in cirrhotic patients admitted to general Intensive Care Units. No assessment of these scores was performed in cirrhotics admitted to specialized Gastroenterology Intensive Care Units (GICUs). AIM to assess the prognostic accuracy of Acute Physiology and Chronic Health Evaluation (APACHE) II, Simplified Acute Physiology Score (SAPS) II, Sequent...

Background and objective Sepsis is a major health burden that leads to significant morbidity mortality. Early diagnosis severity prediction using various scoring systems can reduce the mortality rate, particularly in developing nations. There are two aims of this study. One evaluate prognostic accuracy Sequential Organ Failure Assessment (SOFA) score serum lactate levels patients with sepsis pr...