Our patients with multiple sclerosis (MS) frequently inquire about the safety and efficacy of an annual influenza vaccination. Influenza remains a leading cause of mortality in the United States, with an estimated 20,000 deaths or more annually. Approximately 40% of all adults in the United States are vaccinated annually. The necessity of vaccination is particularly compelling for those with MS...

Objectives: To assess the immunogenicity of Hepatitis B Vaccine in children with thalassemia.
 Study Design: Prospective longitudinal study.
 Place and Duration Study: Pak Emirates Military Hospital, Rawalpindi Pakistan from Aug 2018 to Jan 2019.
 Methodology: After ethical approval informed consent, 150 diagnosed patients thalassemia were selected Thalassemia centre at Hospital ...

Objective: To compare immunogenicity of a recombinant hepatitis B (HB) vaccine in two groups of neonates born in two cities of Iran with different geographic and ethnic backgrounds.   Materials and Methods: Ten micrograms of a recombinant HB vaccine was administered under field condition to Iranian healthy neonates at 0, 1.5 and 9 months intervals. The subjects consisted of two groups of 290 an...

Abstract Background Hepatitis B virus (HBV) vaccine seroprotection rates with conventional aluminum adjuvanted recombinant HBV vaccines (HepB-alum) among people HIV (PWH) are varied. HepB-CpG, a novel vaccine, has shown higher in immunocompetent patients but is not well studied PWH. There no published studies comparing between HepB-alum and HepB-CpG The purpose of this study was to evaluate com...

BACKGROUND AND AIMS The duration of the protection of hepatitis B vaccination for infants and the necessity of a booster dose administration is unknown. The aim of the present study was to evaluate the persistence of seroprotection after hepatitis B virus (HBV) vaccination in order to determine the necessity of a single booster dose in 5- to 7-year-old children. METHODS This clinical trial st...

Coronavirus Disease (COVID-19) as the reemerging disease which first discovered on December 2019 in Wuhan, China. World Health Organization (WHO) has designated COVID-19 a global pandemic March 11th, 2020. Covid-19 is related with climate change influences environment of life cycle SARS-CoV2 vector. With there are no drug choice for until this time, giving vaccination one strategy prevention to...

BACKGROUND Promising clinical data and significant antigen-sparing have been demonstrated for a pandemic H5N1 influenza split-virion vaccine adjuvanted with AS03A, an α-tocopherol-containing oil-in-water emulsion-based Adjuvant System. Although studies using this formulation have been reported, there have been no data for Japanese populations. This study therefore aimed to assess the immunogeni...

From 1982 to 1989, 705 infants born to HBsAg-positive mothers entered the Dutch neonatal hepatitis B vaccination program and received passive-active hepatitis B immunization in three randomized controlled trials testing variations in time of starting active vaccination, dose and type of vaccine, and number of hepatitis B immunoglobulin (HBIg) injections. A meta-analysis of individual patient da...