نتایج جستجو برای: serous tumors
تعداد نتایج: 187057 فیلتر نتایج به سال:
background: recent studies have showed conservative management in selective patients with borderline and malignant ovarian tumors is safe; therefore this management is considered in patients with ovarian tumor who desire to preserve fertility. objective: this study has been performed to evaluate the clinical outcome and fertility in patients with ovarian tumors who were treated conservatively. ...
Introduction Borderline ovarian tumors (BOT) constitute 15% of all epithelial ovarian cancers. As the term borderline implies they clinically behave intermediate between benign and malignant tumors. Synonyms of BOT include tumors of borderline malignancy, tumors of low malignant potential, and atypical proliferative tumors (1). Histologically, the borderline tumors are defined by the presence o...
BACKGROUND OVARIAN CARCINOMAS CONSIST OF AT LEAST FIVE DISTINCT DISEASES: high-grade serous, low-grade serous, clear cell, endometrioid, and mucinous. Biomarker and molecular characterization may represent a more biologically relevant basis for grouping and treating this family of tumors, rather than site of origin. Molecular characteristics have become the new standard for clinical pathology, ...
OBJECTIVES To evaluate the prognostic effect of the Heterogeneous nuclear ribonucleoprotein type M (HNRPM) and Solute carrier 1A5 (SLC1A5) in FIGO-stages I-II epithelial ovarian cancer. METHODS A retrospective cohort study was designed to investigate the prognostic effect of HNRPM and SLC1A5, and the association with clinical-pathologic characteristics in 131 patients with FIGO-stages I-II ep...
The origin of ovarian epithelial tumors is still indistinct. Müllerian and coelomic hypothesis are controversial. Recently, there is also a small number of reports that tubo-peritoneal junction may play an important role in the development of tubo-ovarian tumors. Therefore, we aimed to investigate the relationship between tumors originating from Mullerian epithelium and peritoneal mesothelium, ...
PURPOSE A significant number of women with serous ovarian cancer are intrinsically refractory to platinum-based treatment. We analyzed somatic DNA copy number variation and gene expression data to identify key mechanisms associated with primary resistance in advanced-stage serous cancers. EXPERIMENTAL DESIGN Genome-wide copy number variation was measured in 118 ovarian tumors using high-resol...
Recent morphologic, immunohistochemical, and molecular genetic studies have led to the development of a new paradigm for the pathogenesis and origin of epithelial ovarian cancer based on a dualistic model of carcinogenesis that divides epithelial ovarian cancer into 2 broad categories designated types I and II. Type I tumors comprise low-grade serous, low-grade endometrioid, clear cell and muci...
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