Communications to the Editor phoisphorylation. Additionally, the serum lactate level was measured in one oaf otsr cases early in the hospital course, and it was found to be normal. We believe that if uncoupling of oxidative phosphorylation were primarily responsible for shock and multiple-system organ failure, the serum lactate level should have been markedly elevated. Dr Schmidt correctly poin...

The purpose of this present study was to differentiate transudates and exudates in pleural effusions. Oxidative stress has been associated with various respiratory disorders. Ninety patients of pleural effusions of diverse etiologies were participated in this study. Subjects underwent diagnostic thoracentesis and standard biochemical parameters (total protein, lactate dehydrogenase, glucose, MD...

An unusual isozyme of lactate dehydrogenase, láclate dehydrogenase associated with Kirsten murine sarcoma virus (LDHk) was found in the sera of many patients with malignant tumors, while the sera of healthy persons had little or no such activity. This isozyme was detectable only when assayed in a nitrogen atmosphere, and its activity showed little or no relationship to the total lactate dehydr...

background: long surgery causes hypothermia and increased bleeding and can increase the arterial blood lactate levels during anesthesia. it causes cellular hypoxia and its complications. considering the core temperature of the patient during surgery it can prevent hypoxia. this study aimed to compare the effects of different temperatures on the core temperature and the concentrations of lactate...

Over the past decade, studies of Neisseria gonorrhoeae have shown that in media containing glucose, lactate stimulates metabolism, and this could affect pathogenicity (7, 19). Recently, the probable mechanism of this stimulation has been identified as one that could apply to other pathogens (68). Earlier studies implicated lactate metabolism in the serum resistance of Haemophilus influenzae (30...

Two studies reported here demonstrate a statistically significant association between metastatic cancer and the appearance of the k isozyme of lactate dehydrogenase in serum of affected patients. The first study included 190 coded samples from three types of cancer patients and matched controls; the second included 155 preoperative and 200 postoperative colorectal cancer patients. In the second...

A random retrospective chart review was conducted to document serum carnitine levels on 100 children with autism. Concurrently drawn serum pyruvate, lactate, ammonia, and alanine levels were also available in many of these children. Values of free and total carnitine (p < 0.001), and pyruvate (p = 0.006) were significantly reduced while ammonia and alanine levels were considerably elevated (p <...