نتایج جستجو برای: severe asthma
تعداد نتایج: 386339 فیلتر نتایج به سال:
Background/Objectives. Asthma in older individuals is poorly understood. We aimed to characterize the older asthma phenotype and test its association with obstructive sleep apnea (OSA). Design. Cross-sectional. Setting. Pulmonary and Asthma/Allergy clinics. Participants. 659 asthma subjects aged 18-59 years (younger) and 154 aged 60-75 (older). Measurements. Sleep Apnea scale of Sleep Disorders...
1 Bush A, Hedlin G, Carlsen KH, et al. Severe childhood asthma: a common international approach? Lancet 2008; 372: 1019–1021. 2 Hedlin G, Bush A, Lødrup Carlsen K, et al. Problematic severe asthma in children, not one problem but many: a GALEN initiative. Eur Respir J 2010; 36: 196–201. 3 Lang AM, Konradsen J, Carlsen KH, et al. Identifying problematic severe asthma in the individual child – do...
Background Early recognition of severe asthma may improve its management, modify its natural history by better approaching therapy and helps identifying patients resistant to current asthma therapy. Rhinitis and chronic rhinosinusitis are linked to asthma by clinical, epidemiological and similar inflammatory mechanisms which interrelates upper and lower airways. Evidence for high rate of chroni...
We found the results of the European Network For Understanding Mechanisms Of Severe Asthma (ENFUMOSA) study [1] and its accompanying Editorial [2] very interesting and would like to raise two issues, one regarding classification of subjects, and the other concerning pathogenesis. The ENFUMOSA study defined a group with severe asthma, requiring high-dose inhaled corticosteroids who continued to ...
OBJECTIVE To determine neonatal and maternal outcomes stratified by asthma severity during pregnancy by using the 1993 National Asthma Education Program Working Group on Asthma and Pregnancy definitions of asthma severity. The primary hypothesis was that moderate or severe asthmatics would have an increased incidence of delivery at <32 weeks of gestation compared with nonasthmatic controls. M...
Severe asthma is a major health concern. The allergic (IgE-mediated) form of asthma is well known from a pathogenic viewpoint. We searched the available literature to identify which allergens are most frequently associated with severe, refractory or life threatening asthma. According to the results, molds, pet dander, cockroach and ragweed were more frequently responsible for severe asthma. Thu...
We report the case of an asthmatic patient with blunt trachea and left main bronchus injuries who developed acute severe asthma after surgical repair. Despite medical treatment and ventilatory support, asthma persisted with high airway pressures and severe respiratory acidosis. We proposed venovenous extracorporeal life support for CO(2) removal which allowed arterial blood gas normalization an...
PURPOSE OF REVIEW Asthma is quite common and is better described as a syndrome with a heterogeneous presentation than as a single disease. Although most individuals can be effectively managed using a guideline-directed approach to care, those with the most severe illness may benefit from a more targeted therapy. The review describes our current understanding of how asthma phenotypes (observable...
ATS/ERS statement: asthma control and exacerbations 2 Consistently very poorly controlled asthma increases risk for future severe asthma exacerbations 2 The FDA and safe use of long-acting beta-agonists in the treatment of asthma 2 Thirteen-year follow-up of early intervention with an inhaled corticosteroid in patients with asthma 3 Oral prednisolone for preschool children with acute virus-indu...
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