Introduction: the carcinogenicity of silicone implants has been confirmed in rodents but is not evident in human breast. case report: We report a patient with Li-Fraumeni syndrome who developed bilateral chest wall unclassified sarcomas tightly associated with the capsule of silicone implants placed during treatment for her right breast cancer. conclusion: Our case may suggest that genetic inst...

6. Armaly MF: Ocular tolerance to silicones: 1. Replacement of aqueous and vitreous by silicone fluids. Arch Ophthalmol 68:390, 1962. 7. Lee P, Donovan RH, and Mukai N: Intravitreous injection of silicone: An experimental study. Ann Ophthalmol 1:15, 1969. 8. Foerster MM, Esser J, and Laqua H: Silicone oil and its influence on electrophysiologic findings. Am J Ophthalmol 99:201, 1985. 9. Gregor ...

AIMS To investigate the adhesion characteristics of several intraocular lenses (IOLs) to the simulated and rabbit lens capsule. METHODS Adhesive force to bovine collagen sheets was measured in water with polymethylmethacrylate (PMMA), three piece silicone, and acrylic foldable IOLs. In rabbit eyes, phacoemulsification and IOL implantation were performed. Three weeks later, adhesion between th...

Breast implants have been used for breast reconstruction and augmentation for the last 50 years. There are about 100,000 women in the United Kingdom with silicone implants, of which approximately 60% are for breast reconstruction following mastectomy [1]. Approximately one to two million women have undergone breast implantation in the United States [2]. The silicone Poly Implant Prothèse breast...

PURPOSE To evaluate the outcome of 23 G PPV and ILM peeling with 14% C3F8 compared with silicone oil tamponade in cases of TMHs without spontaneous closure. METHODS A retrospective comparative study included 33 eyes with TMHs; 7 eyes healed spontaneously, and the remaining 26 eyes have been treated with PPV and ILM peeling. Silicone oil was used as a tamponade for children or adults who refus...

PURPOSE The objective of this study was to evaluate and compare the relative durability and complications between the proximal valve polyurethane and distal valve silicone peripherally inserted central catheters (PICCs). METHODS Institutional review board approval was obtained. A total of 326 patients (mean age, 50.4 years) was assigned randomly to receive either a proximal valve polyurethane...

Silicone biofouling release coatings have been shown to be an effective method of combating fouling. Nearly all silicone foul release coatings are augmented with an oil additive to decrease macrofouling attachment strength. This paper addresses the effect of the type of oil that is incorporated into the silicone coating and the type of silicone coating itself (silica vs calcium carbonate filled...

BACKGROUND Colour degradation is a major problem in maxillofacial silicone elastomers. Recent studies have focused on colour stability and the mechanical properties of the silicone elastomers. A colour match is also essential for the acceptance of the prosthesis by the patient. The aim of this study is to assess the colour degradation of the silicone elastomer after being moulded in different c...

Protein drugs such as insulin are almost universally delivered via glass syringes lubricated with silicone oil. It is not uncommon for prefilled syringes (PFS) to become cloudy, which may affect bioavailability or total drug dose. To examine the role, if any, of the silicone oil lubricant in this process, a systematic evaluation of the degree of insulin denaturation and aggregation as a functio...