Parkinson’s disease is a progressive, neurodegenerative disorder of the extrapyramidal nervous system affecting mobility and control skeletal muscular system. Although PD can develop at any age, it begins most commonly in older adults, with peak age onset around 60 years. Levodopa dopamine agonists such as ropinirole are used treatment. This complete literature search was done using Google Scho...

Vitamin D is a liposoluble organic compound that, in addition to calcium metabolism and its effect on the skeletal system, also has numerous other effects organ systems, such as cardiovascular, endocrine, immune, but central nervous system. The primary source of vitamin food animal origin; however, synthesized skin upon exposure sunlight. In this paper, we will present studies corroborating the...

Skeletal muscle comprises the major organ system in our bodies and is effector tissue for fundamental processes, such as movement, breathing glucose homeostasis. However, regeneration can be insufficient to repair injuries or become exhausted by ongoing fiber damage that occurs muscular dystrophy. Cell therapy provide a source of myogenic stem cells repopulate lost fibers an attractive option t...

Skeletal muscle tissue engineering holds great promise for pharmacological studies. Herein, we demonstrated an in vitro drug testing system using tissue-engineered skeletal muscle constructs. In response to epigenetic drugs, myotube differentiation of C2C12 myoblast cells was promoted in two-dimensional cell cultures, but the levels of contractile force generation of tissue-engineered skeletal ...