Background: Sentinel lymph node (SLN) biopsy has become the standard method for assessing the regional lymph node status of patients with skin cancers such as malignant melanoma, squamous cell carcinoma, or extramammary Paget’s disease. Recently, we reported a novel method for detection of SLN in skin cancer patients by real-time fluorescence navigation with indocyanine green (ICG). Objective: ...

OBJECTIVE In our study, we aimed to evaluate retrospectively histopathological diagnoses of children based on their skin biopsies, and determine the prevalence of the disease in question. METHODS Among patients who applied to Medeniyet University Goztepe Training and Research Hospital between January 2011 and February 2014, we retrospectively evaluated demographic data and histopathological d...

INTRODUCTION Leprosy, whose etiologic agent is M. leprae, has its clinical manifestations correlated with distinct immunologic forms. The mechanism of infectivity and dissemination of the disease are not completely known, although the nasal mucosa is supposed to have an important role in pathogenesis. OBJECTIVE To correlate the clinical and bacteriological parameters with that of nasal biopsy...

A reverse transcription (RT)-PCR assay targeting the 16S rRNA of Mycobacterium leprae was developed to detect the organism in clinical specimens. A 171-bp fragment was amplified when M. leprae RNA was used as a template but not when a panel of RNAs from 28 potentially cross-reacting mycobacterial species, seven genera related to Mycobacterium, and three organisms normally found among skin or no...

Calciphylaxis, nowadays called calcific uremic arteriolopathy (CUA), is a rare but life-threatening syndrome characterized by systemic medial calcification and arterial occlusion of the arterioles, leading to skin necrosis. Actually, the pathogenesis of CUA is complex and poorly understood. The vast majority of published cases presented with ulcers. We present a 71-year-old male who was referre...

BACKGROUND Sarcoidosis is a systemic disease characterized by the formation of noncaseating granulomas in various tissues. Cutaneous involvement occurs in 20 to 35 percent of the patients and may be the initial manifestation of the disease. Our study was performed to discriminate the clinical, laboratory, and prognostic differences between patients with specific and nonspecific cutaneous involv...

an adult (two years old) iranian cross-breed ram with alopecia, rough hair coats, thick and wrinkled skin,especially on the face, brisket, scrotum, tail and legs, presented with severe pruritus, poor condition andgeneralized unthriftiness. the animal was referred to the veterinary clinic of shahid bahonar university ofkerman. the vital signs and haematologic indices of the animal were normal. a...

INTRODUCTION: Skin cancer is the most frequent malignant neoplasm in Brazil. Its prognosis directly related to early diagnosis and institution of adequate treatment. The Cancer National Awareness Campaign (SCNAC) an essential tool prevent detect skin lesions. OBJECTIVES: To investigate incidence accuracy dermoscopy patients assessed at SCNAC. METHODS: We conducted a retrospective cohort study u...

BACKGROUND Prilocaine-lidocaine emulsion (EMLA) has been used successfully as a local anesthetic in patients undergoing superficial procedures. OBJECTIVE The purpose of this study was to investigate the analgesic effect of the patch as a local anesthetic for children undergoing a skin biopsy procedure. The effect on both the pain at the injection site and the pain of the biopsy was investigat...

scleroderma is a multisystem autoimmune connective tissue disease, cliaracterized by hardening of the skin. hv had 25 patients in the iranian pediatric unit of rheumatology over 10 years. there was female predominance if.m = 4/1, 80% female, 20% male). the age of onest was from 6 months to 16 years, the mean age being 10 years. the symptoms and signs were: nonpitting edema in 16%, liard skin in...