PURPOSE The aim of this study was to explore the potential contribution to skin damage caused by standard washing and drying techniques used in nursing. DESIGN An experimental cohort design was used, with healthy volunteers (n = 15) receiving 6 different washing and drying techniques to the volar aspect of the forearm. Subjects underwent 3 washing and drying techniques on each arm; each techn...

Separate-sex rearing of slaughter ostriches was investigated as a management strategy to minimize skin damage. Day-old ostrich chicks were divided into three treatment groups; a group of mixed-gender and two single-sex groups, one male and one female. At three months of age, because of the large variation in live weights, the birds were sorted within treatment according to weight. Each gender t...

Helicobacter pylori is probably the commonest bacterial infection worldwide and is now accepted as the cause of gastritis, peptic ulcer, gastric carcinoma, and gastric lymphoma. In the last few years, besides the local gasteroduodenal tissue damage, an association between H.pylori and various extra-intestinal pathologies had been described. Recent studies have suggested that H.pylori infection ...

Ultraviolet B (UVB) radiation induces DNA damage, oxidative stress and inflammation, and suppresses the immune system in the skin, which collectively contribute to skin aging and carcinogenesis. The DNA damage response, including DNA repair, can be regulated by the circadian clock and microRNA (miRNA) expression. The aim of the present study was to evaluate the reparative action of Trichosanthe...

Skin aging is a dynamic process that occurs due to chronological and photo-aging caused by the influence of external factors, especially ultraviolet-UV radiation. Cumulative oxidative stress, formation of free radicals and their adverse effects on biological systems in the skin cells is a common mechanism of both skin aging processes. The formed reactive oxygen species-ROS can lead to the oxida...

BACKGROUND Diabetes is characterized by chronic hyperglycemia, and hyperglycemia can increase reactive oxygen species (ROS) production from the mitochondrial electron transport chain. The formation of ROS in cells induces oxidative stress and activates oxidative damage-inducing genes. There is no research on the protein levels of oxidative damage-related genes AKR1C3 in human diabetic skin. We ...

Autier et al. (1) reported that sun-screen use seems to encourage longer recreational exposure to the sun. We wish to supplement their results with data on the effects of sunscreens and tanning on ultraviolet (UV)-induced DNA damage in human skin. Our data have become available through a recently developed method for measuring UV-induced DNA damage, i.e., cy-clobutane pyrimidine dimers and pyri...

damage. UVB exposure of human skin induces skin alterations, including erythema, which is characteristic of sunburn cells, and prolonged UVB exposure results in the formation of wrinkles, the degradation of matrix molecules, the development of elastosis, and an increased risk of epithelial skin cancer. Keratinocytes are the main target of UV, and play a central role in several responses of phot...

The basic leucine zipper transcription factor, CCAAT/enhancer binding protein (C/EBP ), is abundantly expressed in keratinocytes of the skin; however, its function in skin is poorly characterized. UVB radiation is responsible for the majority of human skin cancers. In response to UVB-induced DNA damage, keratinocytes activate cell cycle checkpoints that arrest cell cycle progression and prevent...