Rosacea is a chronic facial skin condition of unknown cause. It is characterized by marked involvement of the central face with transient or persistent erythema, telangiectasia, inflammatory papules and pustules, or hyperplasia of the connective tissue. Transient erythema, or flushing, is often accompanied by a feeling of warmth. It usually lasts for less than five minutes and may spread to the...

Rosacea is a chronic inflammatory disease with transient and non-transient redness as key characteristics. Brimonidine is a selective α2-adrenergic receptor (AR) agonist approved for persistent facial erythema of rosacea based on significant efficacy and good safety data. The majority of patients treated with brimonidine report a benefit; however, there have been sporadic reports of worsening e...

Background: Rosacea is a chronic inflammatory skin condition associated with four distinct subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular. Purpose: To review the different kinds of management for all subtypes. Methods: We divided rosacea management into three main categories: patient education, skin care, and pharmacological/procedural interventions. Results: Flushing...

Introduction: Erythema nodosum may be the first sign of a systemic disease such as tuberculosis, viral, bacterial or fungal infections such as coccidioidomycosis. Other causes include sarcoidosis, inflammatory bowel disease, cancers, pregnancy/hormone related, idiopathic, and medication side effects. Diagnosing the primary cause of this skin manifestation may help a clinician find the underlyin...

An 87-year-old man was referred to our photobiology unit in August 2015 for the diagnosis and treatment of eczematous lesions involving the sun-exposed areas (face, dorsal aspects of hands, and feet) that he had suffered from for >5 years. He had suffered from hypertension, and had experienced a cerebrovascular accident 10 years previously. Since then, triflusal (300mg twice daily) has been pre...

Because childhood rashes may be difficult to differentiate by appearance alone, it is important to consider the entire clinical presentation to help make the appropriate diagnosis. Considerations include the appearance and location of the rash; the clinical course; and associated symptoms, such as pruritus or fever. A fever is likely to occur with roseola, erythema infectiosum (fifth disease), ...

The flowers of Prunus persica Batsch have been used for skin disorders in East Asia from ancient times. In this investigation, the ethanol extract from this plant material was prepared and several major constituents were isolated. In addition, the protective effects of the extract were evaluated against solar ultraviolet (UV)-induced skin damage using in vivo animal models of UVB-induced erythe...

Visual inspection of intact skin is commonly used when assessing persons for pressure ulcers and bruises. Melanin masks skin discoloration hindering visual inspection in people with darkly pigmented skin. The objective of the project is to develop a point of care technology capable of detecting erythema and bruises in persons with darkly pigmented skin. Two significant hardware components, a co...

Recently, there has been much effort to find effective ingredients which can prevent or retard cutaneous skin aging after topical or systemic use. Here, we investigated the effects of the atomic hydrogen surrounded by water molecules, H(H2O)m, on acute UV-induced responses and as well as skin aging. Interestingly, we observed that H(H2O)m application to human skin prevented UV-induced erythema ...

An estimated 90% of breast cancer patients treated with radiotherapy will develop radiation dermatitis (Harper, 2004). Therapeutic doses of radiation cause persistent skin erythema, desquamation, rash, pain, itching and ulceration increasing risk of infection. Some clinicians suggest radiodermatitis be treated for the life of the patient because of collateral skin damage. Chemotherapy increases...