BACKGROUND Cutaneous sclerosis, a process that results in hardening of the skin, is the hallmark of scleroderma and sclerodermoid disorders. Cutaneous sclerosis is usually classified as secondary or primary, depending on the presence or absence of underlying diseases. Primary cutaneous sclerosis is a feature of idiopathic inflammatory processes that are often associated with autoimmune disorder...

We have investigated the ram-pressure stripping of disk galaxies in clusters at various redshifts and in cluster progenitors; the clusters grow up on a hierarchical clustering scenario. We consider a radially infalling galaxy whose initial position and velocity are given by a spherical collapse model of structure formation. Moreover, since observations show that the intracluster medium (ICM) of...

Aim Stripping is a technique of creating space for correction of crowding by interproximal enamel reduction. This study sought to assess the efficacy of mesial stripping of mandibu-lar deciduous canines for correction of rotated and lingually erupted lateral incisors. Materials and methods This clinical trial was performed on 42 patients with <3 mm mandibular anterior crowding. The required s...

Paint stripping from large steel ships and other metallic surfaces is a major environmental safety, cost, and operational challenge in effectively and efficiently maintaining and refurbishing large structures. Environmental concerns are greatly limiting the possible options. As a result, a hybrid system composed of a waterjet with water recycling and robotic mobile manipulators with scanning br...

We use template stripping to integrate metallic nanostructures onto flexible, stretchable, and rollable substrates. Using this approach, high-quality patterned metals that are replicated from reusable silicon templates can be directly transferred to polydimethylsiloxane (PDMS) substrates. First we produce stretchable gold nanohole arrays and show that their optical transmission spectra can be m...

We assessed the effects of physical and chemical irritants on a profile of acute inflammatory mediators in normal human skin. Skin damage in both cases is accompanied by a flux of inflammatory processes and repair mechanisms, which remain imprecisely understood. We used 10 sequential cellotape strips or topical application of 0.075% capsaicin as skin irritants and characterized the subsequent p...

BACKGROUND In recent years, there has been considerable interest in using botanical agents to prevent skin damage resulting from solar UV-irradiation. Buddleja cordata is a plant that is known as "tepozan". Some people in Mexico use the leaves of this plant to treat tumours, abscesses, sores and burns. The purpose of this study is to investigate the photoprotective properties of Buddleja cordat...

he Eg5 kinesin helps build a bipolar spindle by sliding microtubules past each other at the spindle midzone. On page 473, Ganem and Compton show that bipolarity requires another kinesin, called Kif2a, that localizes to spindle poles. Kif2a is strongly expressed in neuronal cells and is a member of a class of kinesins that depolymerize micro-tubules instead of stepping along their surface. The a...

Atopic dermatitis (AD) is a heterogeneous disease and characterized by dysregulated immune response of diverse cell subtypes, such as Th2, Th22, Th17. Heterogeneity AD can be reasoned varying contribution underlying subsets, observed altered cytokine milieus in the skin. These variations result changes protein expression keratinocytes, including antimicrobial peptides (AMPs). We hypothesize tha...