Analysis of surface skin temperature with an MX Onda contact thermometer (MX Onda, Madrid, Spain) showed a decrease of 2 C in the affected area compared with adjacent healthy skin. Laboratory tests including complete blood count, biochemistry, erythrocyte sedimentation rate, autoimmune studies, cryoglobulins, lupic anticoagulant, and serology for Borrel ia burgdorferi were normal or negative. P...

The effect on the skin of housewives of using a washing product in the home for all cleaning purposes under conditions of maximal exposure has been studied. Tests conducted on over 4,000 housewives showed that detergents containing proteolytic enzymes had no greater effect on the skin than conventional detergents, even when the hand skin condition was initially poor. The same was true in a furt...

BACKGROUND The diagnosis of insect venom allergy and the indication for specific immunotherapy is based on history, skin tests and demonstration of hymenoptera venom specific IgE-antibodies. In cases with contradictory test results additional cellular tests are recommended. OBJECTIVE We evaluated the usefulness of a newly introduced test based on basophil CD63 expression as marker of activati...

INTRODUCTION This multicenter study aimed to evaluate the diagnostic value of 2 cellular tests based on basophil reactivity--the basophil activation test (BAT, Flow-CAST) and the sulfidoleukotriene release assay (CAST-ELISA)--in immediate-type beta-lactam allergy, particularly in patients with a clinical history of allergy and a negative skin test result. MATERIAL AND METHODS In a multicenter...

BACKGROUND Hypersensitivity to contrast media (CMs) may be common and serious. AIM To evaluate the prevalence of CM hypersensitivity, risk factors associated with it and the role of skin testing in its diagnosis. METHODS A structured questionnaire was administered to patients who underwent computed tomography during a 1-year period. Skin tests with CMs, including skin prick tests (SPTs), in...

Fifteen patients with Alzheimer's disease (AD) and 16 age-matched controls underwent skin vessel reactivity tests employing three vasodilating substances with different modes of action: acetylcholine (ACh), nitroprusside, and isoprenaline. The substances were iontophoresed into the skin and the results were mapped through a newly developed laser Doppler perfusion imager. The skin vascular respo...

Laser Doppler flowmetry (LDF) is commonly used in combination with reactivity tests to noninvasively evaluate skin sympathetic nerve activity and skin microvascular function. In manual medicine research, LDF has been used as a marker for global peripheral sympathetic nervous system function, but these results should be considered with caution because skin sympathetic nerve activity physiology i...

A history of pet contact and/or apparent clinical sensitivity was obtained in 65 (55%) of 118 unselected asthmatic children. These 65 children were skin tested and their sera examined for specific IgE using the radioallergosorbent test. Those children who had apparent clinical sensitivities had larger skin test reactions and were more likely to have positive specific IgE results than those with...

Aas, K. (1970). Archives of Disease in Childhood, 45, 221. Bronchial provocation tests in asthma. Bronchial provocation tests are necessary for precise aetiological diagnosis in bronchial asthma. This is illustrated by the results in 9,364 bronchial provocation tests compared with skin tests and nasal tests. The technique of bronchial provocation testing and its interpretation are described in ...

Aas, K. (1970). Archives of Disease in Childhood, 45, 221. Bronchial provocation tests in asthma. Bronchial provocation tests are necessary for precise aetiological diagnosis in bronchial asthma. This is illustrated by the results in 9,364 bronchial provocation tests compared with skin tests and nasal tests. The technique of bronchial provocation testing and its interpretation are described in ...