malformations which occur during the development of the avian body organs can lead to structural and functional abnormalities. most defects are recognized at hatching, but some go undetected until somewhat later. the cause of the majority of animal congenital malformations is unknown. a significant proportion of congenital malformations of unknown cause are likely to have an important genetic c...

holt-oram syndrome (hos) is a developmental disorder inherited in an autosomal-dominant pattern. affected organs are the heart and forelimbs with upper extremity skeletal defects and congenital heart malformation. in this study we present three cases of hos in the same family. in one of these three individuals we detected a transition of c to t (ctg-gtt, v205v) in exon 7 of the tbx5 gene. this ...

Ultrasound phased arrays may offer a method for non-invasive deep brain surgery through the skull. In this study a hemispherical phased array system is developed to test the feasibility of trans-skull surgery. The hemispherical shape is incorporated to maximize the penetration area on the skull surface, thus minimizing unwanted heating. Simulations of a 15 cm radius hemisphere divided into 11, ...

Sutures form an integral part of the functioning skull, but their role has long been debated among vertebrate morphologists and palaeontologists. Furthermore, the relationship between typical skull sutures, and those involved in cranial kinesis, is poorly understood. In a series of computational modelling studies, complex loading conditions obtained through multibody dynamics analysis were impo...

Neurologic sequalae of Noonan syndrome have been postulated in the literature. A topic significance is role RASopathy shared pathophysiology Syndrome and Chiari I malformation. In this unique case report, we present a patient with concomitant 4th ventricular outflow obstruction. The highlights importance close clinical suspicion population. We utilize to delve into intricacies known encourage o...

Articles you may be interested in An MR-compatible phantom for evaluating the propagation of high intensity focused ultrasound through the skull AIP Conf. Experimental and numerical investigation of ultrasonic transmission through the skull bone and associated temperature rise Focusing of therapeutic ultrasound through a human skull: A numerical study Linearity of sound transmission through the...

The human head is a combination of the variety of different tissues of the skull, brain, cerebellar, brainstem, cerebrospinal fluid (CSF), and neck bone, etc. The differences of both skull and neck bone combined reaction and pure skull reaction are discussed in the analysis. Finite element method (FEM) is employed not only to analyze the natural vibration modes but also to understand the reacti...

A strongly ossified and rigid skull roof, which prevents parietal kinesis, has been reported for the adults of all amphibian clades. Our μ-CT investigations revealed that the Buresch's newt (Triturus ivanbureschi) possess a peculiar cranial construction. In addition to the typical amphibian pleurokinetic articulation between skull roof and palatoquadrate associated structures, we found flexible...

In order to evaluate the usefulness in deciding surgical indication in secondary hyperparathyroidism (SHP), 67Ga scintigraphy was performed in 37 patients of SHP before parathyroidectomy (PTx). The radionuclide accumulation in skull and submandible was classified into 4 patterns (skull-submandibular pattern, skull pattern, submandibular pattern and normal pattern). Serum alkaline phosphatase le...