Motivated by the analysis of gene expression data, we develop a new unsupervised modeling technique. Specifically, we study how such data can be modeled via sparse matrix factorization (SMF). Unsupervised modeling using constrained matrix factorization has been studied by Lee and Seung [1, 2, 3]. Under this approach, one unveils structure in a data matrix A ∈ Rn×d, by approximating it as a prod...

The ABCD matrix method is used to simplifying the theoretical coupling efficiency calculation of Elegant Hermite-Cosh-Gaussian (EHChG) laser beams to a Single Mode Fiber (SMF) with a quadric lens formed on the tip. The integrals of coupling efficiency relation are calculated numerically by Boole method. Meanwhile, the structure parameters of surface-lensed fiber are optimized in numerical simul...

Caenorhabditis elegans ftn-1 and ftn-2, which encode the iron-storage protein ferritin, are transcriptionally inhibited during iron deficiency in intestine. Intestinal specific transcription is dependent on binding of ELT-2 to GATA binding sites in an iron-dependent enhancer (IDE) located in ftn-1 and ftn-2 promoters, but the mechanism for iron regulation is unknown. Here, we identify HIF-1 (hy...

An in-line Mach–Zehnder-interferometer-based two-dimensional (2-D) micrometric displacement sensor was fabricated by inserting a polarization maintaining fiber (PMF) with a length of 1 cm between two conventional singlemode fibers (SMFs). The left end of the PMF was mismatch fusion spliced with an SMF. The right end of the PMF was connected to another SMF without fusion splicing. Two independen...

To establish the role of the metabolic state in the pathogenesis of polyneuropathy, an age- and sex-matched, longitudinal study in rats fed high-fat and high-sucrose diets (HFSD) or high-fat, high-sucrose and high-salt diets (HFSSD) relative to controls was performed. Time courses of body weight, systolic blood pressure, fasting plasma glucose (FPG), insulin, free fatty acids (FFA), homeostasis...

Abstract In this work, a hybrid sensor based on silica capillary in balloon-like shape for simultaneous measurement of displacement and temperature is proposed the first time, to best our knowledge. The fabricated by splicing segment hollow core fiber between two single mode fibers (SMF) bending balloon with at top-center position. transmission scheme, SMF-capillary-SMF configuration excites an...

(SSF) is an economical alternative technique to submerged fermentation (SmF) for large scale production of industrial enzymes, where raw materials and processing is cheap with reduced chemical cost and less processing risk. It is defined as ‘the growth of microorganisms (mainly fungi) on moist solid materials in the absence of free flowing water’ [1]. This technique uses agricultural substrates...

The cost of cellulase enzymes has limited the feasibility of producing ethanol from fibrous biomass. Traditional submerged fermentation (SmF) was compared to an alternative method of producing cellulase, solid state cultivation (SSC). Results from an economic analysis indicated that the unit costs for cellulase enzyme production were $15.67 (The prices are all 2004 prices in this article, excep...