نتایج جستجو برای: snp309
تعداد نتایج: 201 فیلتر نتایج به سال:
There has been considerable progress in analyzing p53 pathway integrity in CLL. Routine fluorescent in situ hybridization (FISH) analysis detects deletion of the region of chromosome 17 (17p13 ), which includes the gene (TP53) coding for p53. 17p13 is a powerful predictor of resistance to therapy with purine analogues and alkylating agents and poor prognosis in CLL. Approximately 80% of CLL pat...
BACKGROUND The commonly held view of the tumor suppressor p53 is as a regulator of cell proliferation, apoptosis and many other biological processes as well as external and internal stress responses. Mdm2 SNIP309 is a negative regulator of p 53. Therefore, this study aimed to determine the correlation between the patterns of Mdm2 SNIP 309 and the inflammation grading of Helicobacter pylori asso...
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