3D cultures have gained attention in the field of regenerative medicine for their usefulness as in vitro model of solid tissues. Bottom-up technology to generate artificial tissues or organs is prospective and an attractive approach that will expand as the field of regenerative medicine becomes more translational. We have characterized c-kit positive cardiac stem cells after long-term cultures ...

Hepatitis C virus (HCV) is known for its oncogenic potential and has been found to be associated with hepatocellular carcinoma (HCC) and non-Hodgkin lymphoma. It has also been postulated that HCV may play a role in the development of other extrahepatic solid tumors of other organs of the body since it has been isolated from the vessel wall, kidney, and oral mucosa. In this article, we have revi...

It seems solid tumors are developing smart organs with specialized cells creating specified bio-territory, the so called "tumor microenvironment (TME)", in which there is reciprocal crosstalk among cancer cells, immune system cells and stromal cells. TME as an intricate milieu also consists of cancer stem cells (CSCs) that can resist against chemotherapies. In solid tumors, metabolism and vascu...

Transplantation Surgery has undergone a great development during the last thirty years and the survival of solid organ recipients has increased dramatically. Osteo-articular diseases such as osteoporosis, fractures, avascular bone necrosis and osteoarthritis are relatively common in these patients and joint arthroplasty may be required. The outcome of hip arthroplasty in patients with osteonecr...

Many solid or semi-solid tissues have ultra-short or short T2* components that make them virtually “invisible” to standard MRI techniques. For this reason, methods such as ultra-short echo time (UTE) techniques were developed to investigate and detect some of these short and ultra-short time components. Here we report on the development and implementation of a novel version of the Single Point ...

INTRODUCTION Kaposi's sarcomas have been associated with different conditions of immunosuppression and are also known to be a typical complication of solid organ transplantations. CASE PRESENTATION We report the case of a 65-year-old Turkish man with a history of heart transplantation 10 months ago who presented for clarification of his dyspnea. The patient had a known history of chronic obst...

incidence of rejection compared with other solid organs, and spontaneous acceptance of the liver graft with successful discontinuation of immunosuppression has been reported in nearly 20% of LT recipients [10,11]. Multiple studies have suggested the protective effect of the liver allograft in Simultaneous Liver-Kidney Transplantation (SLKT) compared with recipients of isolated renal transplants...

BACKGROUND: Abdominal tuberculosis (TB) is endemic in the developing world and is reemerging in the West. Since computed tomography (CT) has the ability to demonstrate changes in the peritonium, mesentry, lymphnodes, bowel and solid organs and is being increasingly used for primary evaluation of abdominal conditions, it is important to be familiar with the CT features of the disease. METHODS: C...

serovar-specific real-time pcr for salmonella enterica serovar enteritidis (s. enteritidis) was conductedto detect the genomic dna of s. enteritidis from laying goose after subcutaneous vaccination at differenttime points. indirect fluorescent antibody (ifa) technique and immunohistochemical localization wereemployed to validate the results. the results showed that s. enteritidis was consistent...

three-hundred and twenty 7-day-old ross 308-strain broiler chickens were fed diets containing 0 or 125 ppb aflatoxin b 1 (afb1) from 7 to 28 days of age. sodium bentonite (0.5%), yeast (saccharomyces cervisiae) 0.2%, hydrated sodium calcium aluminosilicate (hscas) (0.5%), ammonia (0.5%), formycine (0.1%), and toxiban (0.1%) were added to the basal diet, as fed basis to determine the effects of ...