OBJECTIVE To investigate the significance of circulating adhesion molecules associated with leucocyte-endothelial cell interactions in asthma, serum levels of soluble E (sE)-selectin, soluble P (sP)-selectin, soluble L (sL)-selectin, and soluble vascular cell adhesion molecule-1 (sVCAM-1) were measured in mild, moderate and severe asthma. METHOD Serum levels of sE-selectin, sP-selectin, sL-se...

Soil incubation and pot experiments were conducted to follow the sorption processes of added phosphorus (P) fertiliser using radioisotope tracer technique. Increasing doses P (40, 80, 160, 320 mg P/kg soil) Chernozem Arenosol incubated for 1, 3, 13 weeks. After incubation, perennial ryegrass (Lolium perenne L.) was sown in one group pots, experiment had been continuing another 9 The yield, gras...

in order to investigate the effect of partial replacement of barley starch with beet pulp soluble fiber with or without roasted canola seed on apparent nutrient digestibility, dry matter intake, daily weight gain, feed conversion ratio and rumenal ph 24 arabian male lambs were used for 84 days in a completely randomized design with a 2×2 factorial arrangement. treatments had no significant effe...

BACKGROUND Atrial fibrillation is associated with increased risk of stroke and thromboembolism, possibly by conferring a prothrombotic or hypercoagulable state. However, it is unclear whether or not this differs in the clinical subgroups of chronic atrial fibrillation patients, that is, in those with paroxysmal, persistent or permanent atrial fibrillation. We therefore hypothesized that: (i) th...

OBJECTIVE The CD40/CD40 ligand pathway mediates inflammatory processes important in atherogenesis and the formation of the intraplaque lipid pool. We tested the hypothesis that plasma levels of soluble CD40 ligand are elevated in patients with evidence of a lipid pool on high-resolution magnetic resonance imaging (MRI) of carotid stenoses. METHODS AND RESULTS We recruited 49 patients with evi...

BACKGROUND The activation of c-Met has been associated with both primary and acquired resistance to EGFR-TKI therapy in NSCLC patients. Thus, c-Met status during EGFR-TKI therapy should receive much attention. RESULTS Forty-nine patients were selected as training cohort and 52 cases as validation cohort. With disease progression, IHC results showed that 37 (75.5%) of the patients were tissue ...

BACKGROUND Goeckerman's therapy (GT) of psoriasis is based on daily application of pharmacy grade coal tar on affected skin with subsequent exposure to UV light. Disturbances in angiogenic activity are characteristic for the immunopathogenesis of psoriasis. The aim of study was to evaluate the influence of GT of psoriasis on proinflammatory and angiogenic activities expressed as changes in leve...

PURPOSE Cytotoxic lymphocytes interact with human tumor cells via the activating immunoreceptor NKG2D, recognizing a variety of stress-associated MIC and ULBP surface molecules. However, tumors can escape from this immunosurveillance by shedding NKG2D ligands (NKG2DL), rendering the soluble products detectable in patients' sera. EXPERIMENTAL DESIGN To elucidate the clinical significance of NK...

Phosphorus (P) surplus on dairy farms, especially confined operations, contributes to P buildup in soils with increased potential for P loss to waters. One approach to reduce P surplus and improve water quality is to optimize P feeding and improve P balance on farms. Here we report how varying P concentrations in lactating cow diets affects the amount as well as the chemical forms and fraction ...