نتایج جستجو برای: spermatogonial stem cells
تعداد نتایج: 1506439 فیلتر نتایج به سال:
The ability of adult stem cells to reside in a quiescent state is crucial for preventing premature exhaustion of the stem cell pool. However, the intrinsic epigenetic factors that regulate spermatogonial stem cell quiescenceare largelyunknown.Here,we investigate inmicehowDNA methyltransferase 3-like (DNMT3L), an epigenetic regulator important for interpreting chromatin context and facilitating ...
the stem cells can be considered as the miracle of creation, because, they are a major reservoir of the bioactive factors, molecules and cells. these reservoir cells play a major role in development and growth of the tissues and organs. regardless of the differences in differentiation capacity of embryonic and adult stem cells, both the cells are rich sources of stem cells with therapeutic appl...
Recent studies have reported that induced pluripotent stem (iPS) cells from mice and humans can differentiate into primordial germ cells. However, whether iPS cells are capable of producing male germ cells is not known. The objective of this study was to investigate the differentiation potential of mouse iPS cells into spermatogonial stem cells and late-stage male germ cells. We used an approac...
The ability of adult stem cells to reside in a quiescent state is crucial for preventing premature exhaustion of the stem cell pool. However, the intrinsic epigenetic factors that regulate spermatogonial stem cell quiescenceare largelyunknown.Here,we investigate inmicehowDNA methyltransferase 3-like (DNMT3L), an epigenetic regulator important for interpreting chromatin context and facilitating ...
Abstract Background Nano-fibrous scaffolds provide a three-dimensional matrix that guides sufficient orientation of seeded cells similar to natural niche. In this research, we designed silk scaffold improve the differention mouse spermatogonial stem spermatogenic cell lines. Spermatogonial were collected from neonatal (2–6 days) testes ( n =60) using two steps mechanical and enzymatic method. C...
Introduction: In the present study, we assessed the effects of β-carotene on Titanium oxide Nanoparticle (TNP) induced mouse Spermatozoon Stem Cells (SSCs) apoptosis, at molecular level. Methods: After isolation from cryptorchid mouse testis and characterization, spermatogonial stem cells were divided into four groups. In the control group, spermatogonial cells were cultured in &alp...
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