نتایج جستجو برای: spindle loading

تعداد نتایج: 102684  

Journal: :Acta biomaterialia 2012
Ramon B Montero Ximena Vial Dat Tat Nguyen Sepehr Farhand Mark Reardon Si M Pham Gavriil Tsechpenakis Fotios M Andreopoulos

Current therapeutic angiogenesis strategies are focused on the development of biologically responsive scaffolds that can deliver multiple angiogenic cytokines and/or cells in ischemic regions. Herein, we report on a novel electrospinning approach to fabricate cytokine-containing nanofibrous scaffolds with tunable architecture to promote angiogenesis. Fiber diameter and uniformity were controlle...

Journal: :Journal of cell science 1981
P J Sillers A Forer

In meiosis-I crane-fly spermatocytes 3 autosomal half-bivalents move to each pole in anaphase while the 2 sex-chromosomal univalents remain at the equator. The sex chromosomes move to opposite poles only after the autosomes reach the poles; the sex chromosomes start to move polewards about 25 min after the autosomal half-bivalents have begun to move. We irradiated portions of single autosomal s...

Journal: :Current Biology 2004
Iva M Tolić-Nørrelykke Leonardo Sacconi Geneviève Thon Francesco S Pavone

In eukaryotic cells, proper position of the mitotic spindle is necessary for successful cell division and development. We explored the nature of forces governing the positioning and elongation of the mitotic spindle in Schizosaccharomyces pombe. We hypothesized that astral microtubules exert mechanical force on the S. pombe spindle and thus help align the spindle with the major axis of the cell...

2011
Deping Liu Hang Zhang Zheng Tao Yufeng Su

This paper presents a method to investigate the characteristics of a high-speed motorized spindle system. The geometric quality of high-precision parts is highly dependent on the dynamic performance of the entire machining system, which is determined by the interrelated dynamics of machine tool mechanical structure and cutting process. This performance is of great importance in advanced, high-p...

2011
Marina L. Ellefson Francis J. McNally

In animals, the female meiotic spindle is positioned at the egg cortex in a perpendicular orientation to facilitate the disposal of half of the chromosomes into a polar body. In Caenorhabditis elegans, the metaphase spindle lies parallel to the cortex, dynein is dispersed on the spindle, and the dynein activators ASPM-1 and LIN-5 are concentrated at spindle poles. Anaphase-promoting complex (AP...

2015
Ilaria Scarfone Marianna Venturetti Manuel Hotz Jette Lengefeld Yves Barral Simonetta Piatti Sue L Jaspersen

The asymmetrically dividing yeast S. cerevisiae assembles a bipolar spindle well after establishing the future site of cell division (i.e., the bud neck) and the division axis (i.e., the mother-bud axis). A surveillance mechanism called spindle position checkpoint (SPOC) delays mitotic exit and cytokinesis until the spindle is properly positioned relative to the mother-bud axis, thereby ensurin...

2014
Hui Men Selina Chin Karandeep Nandra Joanna Clark Viji M. Draviam

INTRODUCTION During cell division, the mitotic spindle captures chromosomes and segregates them into two equal sets. The orientation and position of the mitotic spindle is important because the spindle equator becomes the plane of cell division. For instance, in a columnar cell with apical and basal polarity, if the spindle pole-to-pole axis orients along the cell’s long axis, the cell will div...

Journal: :Tissue engineering. Part A 2011
Stavros Thomopoulos Rosalina Das Victor Birman Lester Smith Katherine Ku Elliott L Elson Kenneth M Pryse Juan Pablo Marquez Guy M Genin

Although much is known about the effects of uniaxial mechanical loading on fibrocartilage development, the stress fields to which fibrocartilaginous regions are subjected to during development are mutiaxial. That fibrocartilage develops at tendon-to-bone attachments and in compressive regions of tendons is well established. However, the three-dimensional (3D) nature of the stresses needed for t...

Journal: :Physical review 2022

We construct a family of multidyonically charged and rotating supersymmetric ${\mathrm{AdS}}_{2}\ifmmode\times\else\texttimes\fi{}\mathrm{\ensuremath{\Sigma}}$ solutions $D=4$, $\mathcal{N}=4$ gauged supergravity, where $\mathrm{\ensuremath{\Sigma}}$ is sphere with two conical singularities known as spindle. argue that these arise near horizon limits extremal dyonically accelerating black holes...

Journal: :The Journal of Cell Biology 2007
Caitlin Sedwick

Structure of the meiotic spindle T he meiotic spindle is made up of shorter microtubules than previously believed, suggest results from Ge Yang, Gaudenz Danuser (Scripps Research Institute, La Jolla, CA), Ben Houghtaling, Tarun Kapoor (Rockefeller University, New York, NY), and colleagues. Current models of the spindle, as a bipolar array of overlapping fi laments extending from opposite spindl...

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