نتایج جستجو برای: sporobolomyces
تعداد نتایج: 261 فیلتر نتایج به سال:
Neuroblastoma is a common childhood tumor. Vincristine (VCR), an alkaloid extracted from Catharanthus roseus, is commonly used in combination chemotherapy. However, the mechanisms of VCR-induced neuroblastoma cell death are not clear. The aim of this study was to investigate the impact of VCR on mitosis and apoptosis of SH-SY5Y neuroblastoma cells...
High intake of dietary fructose has been shown to exert a number of adverse metabolic effects in humans and experimental animals. The aim of the present study was to investigate whether Catharanthus roseus (L.) G. Don (Apocynaceae) leaf powder alleviates high-fructose diet-induced insulin resistance and oxidative stress in rats. Adult male Wistar rats of body weight around 200 g were divided in...
Simple Sequence Repeats (SSRs) of polypurine-polypyrimidine type motifs occur very frequently in the 5' flanks of genes in plants and have recently been implicated to have a role in regulation of gene expression. In this study, 2 accessions of Catharanthus roseus having (CT)8 and (CT)21 varying motifs in the 5'UTR of Tryptophan decarboxylase (Tdc) gene, were investigated for its role in regulat...
Hydroxylation of tabersonine at the C-16 position, catalyzed by tabersonine 16-hydroxylase (T16H), initiates the synthesis of vindoline that constitutes the main alkaloid accumulated in leaves of Catharanthus roseus. Over the last decade, this reaction has been associated with CYP71D12 cloned from undifferentiated C. roseus cells. In this study, we isolated a second cytochrome P450 (CYP71D351) ...
Diabetes has been known since ages in Ayurveda by Shushruta. It is a chronic metabolic disorder which results in an increased cane of sugar in blood. In the present investigation phytochemical screening of pollens of some selected plants with known antidiabetic properties was carried out like Catheranthus roseus, Momordica charentia, Butea monosperma and Syzygium cuminii. As pollen is very impo...
BACKGROUND An accurate assessment of transcription 'rate' is often desired to describe the promoter activity. In plants, isolation of transcriptionally active nuclei and their subsequent use in nuclear run-on assays has been challenging and therefore limit an accurate measurement of gene transcription 'rate'. Catharanthus roseus has emerged as a model medicinal plant as it exhibits an unsurpass...
Two direct HPLC analytical methods for the screening of the major indole alkaloids of Catharanthus roseus hairy roots and their iridoid precursors have been developed. Photodiode array and fluorescence detection were performed. The separation was achieved on a reversed-phase C18 column. The first method allowed the separation of catharanthine, serpentine, tabersonine, vindoline, vinblastine, an...
Dehydrodiconiferyl alcohol glucosides (DCGs) are derivatives of the phenylpropanoid pathway that have been isolated from Catharansus roseus L. (Vinca rosea) crown gall tumors. Fractions containing purified DCGs have been shown previously to promote the growth of cytokinin-requiring tissues of tobacco in the absence of exogenous cytokinins. In this study, we utilized synthetic DCG isomers to con...
The search for useful foodstuffs, dyes, medicinal agents, and other materials from plants, animals, or minerals is as old as civilization itself. It should not be surprising, therefore, to learn that all pharmacological prototypes originate from one of these three kingdoms. The alkaloids, nitrogen-containing plant bases, notwithstanding the advent of antibiotics and many valuable synthetic drug...
In this study the effect of responses of Catharanthus roseus to NaCl stress has been explored. Periwinkle plants were exposed to different concentrations of salt and the effect of treatment on germination, growth parameter and antioxidative defense system investigated. Seeds were presoaked in solutions with different salinity after sterilization. Experimental samples irrigated once every two da...
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