نتایج جستجو برای: sprouting
تعداد نتایج: 4649 فیلتر نتایج به سال:
RATIONALE The Notch pathway stabilizes sprouting angiogenesis by favoring stalk cells over tip cells at the vascular front. Because tip and stalk cells have different properties in morphology and function, their transcriptional regulation remains to be distinguished. Transcription factor Sox17 is specifically expressed in endothelial cells, but its expression and role at the vascular front rema...
Drosophila tracheal terminal branches are plastic and have the capacity to sprout-out projections towards oxygen-starved areas, in a process analogous to mammalian angiogenesis. It was previously shown that this sprouting response involves the upregulation of the FGF homolog Branchless in hypoxic tissues, which binds its receptor Breathless on tracheal cells, thereby attracting the outgrowth of...
A critical property of biomaterials for use in regenerative medicine applications is the ability to promote angiogenesis, the formation of new vascular networks, to support regenerating tissues. Recent studies have demonstrated that a complex interplay exists between biomechanical and biochemical regulators of endothelial cell sprouting, an early step in angiogenesis. Here, we use a microfluidi...
Tumor-mobilized bone marrow–derived CD11bþ myeloid cells promote tumor angiogenesis, but how and when these cells acquire proangiogenic properties is not fully elucidated. Here, we show that CD11bþ myelomonocytic cells develop proangiogenic properties during their differentiation from CD34þ hematopoietic progenitors and that placenta growth factor (PlGF) is critical in promoting this education....
CAP23 is a major cortical cytoskeleton-associated and calmodulin binding protein that is widely and abundantly expressed during development, maintained in selected brain structures in the adult, and reinduced during nerve regeneration. Overexpression of CAP23 in adult neurons of transgenic mice promotes nerve sprouting, but the role of this protein in process outgrowth was not clear. Here, we s...
*Rummler, LS; *Palispis, WA; *Truong, LN; *Chao, T; *Rowshan, K; +*Gupta, RG +*University of California Irvine, Irvine, CA [email protected] INTRODUCTION: Chronic nerve compression (CNC) injuries, such as carpal tunnel syndrome, are common orthopaedic conditions. Until recently, little has been known about the cellular and molecular changes after CNC injury. Acute nerve injuries, like axotomy and...
One potential mechanism of temporal lobe epilepsy is recurrent excitation of dentate granule cells through aberrant sprouting of their axons (mossy fibers), which is found in many patients and animal models. However, correlations between the extent of mossy fiber sprouting and seizure frequency are weak. Additional potential sources of granule cell recurrent excitation that would not have been ...
Growing potato tubers or freshly harvested mature tubers have a dormant apical bud. Normally, this dormancy is spontaneously broken after a period of maturation of the tuber, resulting in the growth of a new sprout. Here it is shown that in in vitro-cultured growing and maturing tubers, ethanol can rapidly break this dormancy and re-induce growth of the apical bud. The in vivo promoter activity...
AIMS To investigate the growth of salmonellae on sprouting alfalfa seeds as affected by the inoculum size, microbial load and Pseudomonas fluorescens 2-79. METHODS AND RESULTS Alfalfa seeds pre-inoculated with < or =10(1)-10(3) CFU g(-1) of salmonellae and with or without Ps. fluorescens 2-79 were sprouted in glass jars and the population of salmonellae were determined daily for up to 6 days....
Winter dormancy has been extensively studied in many plants, while much less information is available for summer dormancy. Narcissus tazetta var. chinensis is characterized by a prolonged period of summer dormancy during the annual cycle. In the present study, we characterized the nature of dormancy in the controlled growth conditions and investigated the effects of temperature and ethylene on ...
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