pilonidal disease consists of a hair-containing sinus or abscess occurring most frequently in intergluteal cleft. this disease is generally benign. although very uncommon entity, it seems reasonable to be aware of possible malignancy in longstanding cases. we report a case of squamous cell carcinoma in a 52- year-old man, with a prolonged history of pilonidal disease and ulceration since 3 mont...

myiasis is the condition of infestation of the body by fl y larvae (maggots). the deposited eggs develop into larvae, which penetrate deep structures causing adjacent tissue destruction. it is an uncommon clinical condition, being more frequent in tropical countries and hot climate regions, and associated with poor hygiene, suppurative oral lesions, alcoholism and senility. the diagnosis of myi...

snus (nass) is a form of snuff used in a similar manner to american dipping tobacco, but it does not typically result in a need for spitting. possible hazards associated with this material include malignant and premalignant lesions in the oral cavity and gastrointestinal tract. the use of smokeless tobacco has increased in the middle east in recent decades, particularly among teenagers and youn...

aquatic plants have been used prevalently in china since 3000 years ago due to having various chemical compounds for diseases prevention and cure. dunaliella salina is one of the micro algae in marine ecosystems containing beta-carotene, retinal, apocarotenoides, ketones, aldehydes and epoxides which enable it to absorb free radicals and produce singlet oxygen.  in many studies, the anti-cancer...

Many types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral squamous cell carcinomas (OSCCs) develop from pre-malignant lesions and conditions. Despite adv...

Pilonidal disease consists of a hair-containing sinus or abscess occurring most frequently in intergluteal cleft. This disease is generally benign. Although very uncommon entity, it seems reasonable to be aware of possible malignancy in longstanding cases. We report a case of squamous cell carcinoma in a 52- year-old man, with a prolonged history of pilonidal disease and ulceration since 3 mont...

Unlike the primary tracheal tumors, squamous cell carcinoma of trachea is common, especially in smokers. This type of tumor has a low rate of survival and it is diagnosed too late on account of late presentation of its signs. The treatment of choice is surgical removal followed by adjuvant radiotherapy; Primary radiotherapy is the appropriate treatment in inoperable cases. In this study, we pre...

The tubulin polymerization and Src kinase signaling inhibitor tirbanibulin is being investigated as a topical treatment for actinic keratosis, precursor of squamous-cell carcinoma.