The ANTARES (Astronomy with a Neutrino Telescope and Abyss environmental RESearch) Collaboration constructed and deployed the world’s largest operational underwater neutrino telescope, optimised for the detection of Cherenkov light produced by neutrino-induced muons. The detector has an effective area of about 0.1 km and it is a first step towards a kilometric scale detector. The detector consi...

P-terphenyl (PT) and tetraphenyl-butadiene (TPB) have been investigated as possible wavelength shifting materials for use in Ring Imaging Cherenkov (RICH) detectors. Wavelength shifting films made out of these organic molecules absorb light in the UV region and re-emit fluorescence photons at larger wavelength. Used on top of photomultiplier tubes (PMT), they therefore can enhance the quantum e...

We present the most recent advances in photo-detector design employed in time of flight positron emission tomography (ToF-PET). PET is a molecular imaging modality that collects pairs of coincident (temporally correlated) annihilation photons emitted from the patient body. The annihilation photon detector typically comprises a scintillation crystal coupled to a fast photo-detector. ToF informat...

The success of early imaging cameras in ground based Ĉerenkov astronomy has led to demand for increased imaging resolution. New camera designs, both proposed and already built, contain many hundreds of photomultiplier tubes. In this paper we present a low cost system based on commercially available analogue switches which reduces the number of charge analogue to digital converters (ADCs) needed...

We describe a CMOS-based micro-system for time-resolved fluorescence lifetime analysis. It comprises a 16 × 4 array of single-photon avalanche diodes (SPADs) fabricated in 0.35 μm high-voltage CMOS technology with in-pixel time-gated photon counting circuitry and a second device incorporating an 8 × 8 AlInGaN blue micro-pixellated light-emitting diode (micro-LED) array bump-bonded to an equival...

Recently developed multipixel Geiger-mode avalanche photodiodes (G-APDs) are very promising candidates for the detection of light in medical imaging instruments (e.g. positron emission tomography) as well as in high-energy physics experiments and astrophysical applications. G-APDs are especially well suited for morpho-functional imaging (multimodality PET/CT, SPECT/CT, PET/MRI, SPECT/MRI). G-AP...

A high sensitivity, high resolution brain PET scanner has been developed. The scanner comprises 58 rows of 320 4 x 4 x I O mm3 gadolinium orthosilicate (GSO) crystals, coupled to a continuous light guide that is sampled by 288 39-mm photomultiplier tubes in a hexagonal grid. A distortion removal algorithm has been developed to remove position non-linearities and to identify individual crystal r...

this study aims to numerically investigate on the crashworthiness of thin-walled square tubes by consideration of 3-d oblique loading. in this type of loading, direction of loading is defined by using two spatial angles relative to the position of the tube. to this aim, finite element (fe) analysis is employed to simulate the loading for 8 different numerical models with different loading orien...

Description of the technology Flow cytometry traditionally uses fluorochrome-labeled probes, such as antibodies, to identify cells expressing the targets of those probes. A sample stream carries single cells in suspension past a laser, exciting the fluorochromes, with quantitation of the emitted fluorescent signals from each cell via optical filters and photomultiplier tubes [1]. In mass cytome...