AIMS In patients with ST-elevation myocardial infarction (STEMI) scheduled for primary percutaneous coronary intervention (primary PCI), acute risk-assessment may be valuable for tailoring of adjunctive therapy at the time of coronary intervention. The present study was designed to quantify pre-, per-, and post-interventional ST-changes, to evaluate whether a pre-specified continuous ST-monitor...

AIMS The prognostic value of admission troponin T (tnT) levels and the resolution of the ST-segment elevation in ST-elevation myocardial infarction (STEMI) is well established. However, the combination of these two early available markers for predicting risk has not been evaluated. METHODS AND RESULTS We evaluated 516 patients with fibrinolytic treated STEMI from the ASSENT-2 and ASSENT-PLUS ...

inhibitor to reduced dose thrombolytic therapy significantly improved myocardial perfusion as assessed by ST segment resolution. Thus, this simple tool (that all clinicians can use by simply obtaining a 12-lead ECG 90 min after the start of thrombolysis — and comparing it to the baseline ECG), allows determination of several key aspects of response to therapy and assessment of prognosis. The se...

STUDY OBJECTIVE Sgarbossa's rule, proposed for the diagnosis of acute myocardial infarction in the presence of left bundle branch block, has had suboptimal diagnostic utility. We hypothesize that a revised rule, in which the third Sgarbossa component (excessively discordant ST-segment elevation as defined by ≥5 mm of ST-segment elevation in the setting of a negative QRS) is replaced by one defi...

BACKGROUND Air pollution is associated with greater cardiovascular event risk, but the types of events and specific persons at risk remain unknown. This analysis evaluates effects of short-term exposure to fine particulate matter air pollution with risk of acute coronary syndrome events, including ST-segment elevation myocardial infarction, non-ST-segment elevation myocardial infarction, unstab...

Our primary study aim was to examine extent of, and factors associated with, delay in seeking medical care in a large multinational registry of patients with acute myocardial infarction (AMI) and unstable angina pectoris. A secondary goal was to examine the relation between duration of prehospital delay and receipt and timing of coronary reperfusion strategies. Investigators from 14 countries a...

Correspondence to: Professor Keith A A Fox, Cardiovascular Research Unit, Centre for Cardiovascular Science, University of Edinburgh, Chancellor’s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK; [email protected] _________________________ A cute coronary syndrome (ACS) describes a spectrum of clinical conditions ranging from ST segment elevation myocardial infarction (MI) to non-S...

BACKGROUND New guidelines recommend early invasive evaluation and treatment for most patients with acute myocardial infarction--including patients with myocardial infarction without ST elevation in the ECG. This study examines compliance with the new guidelines at Sørlandet Hospital Arendal. MATERIAL AND METHOD All patients admitted to Sørlandet Hospital Arendal with acute myocardial infarcti...

abstract background: brugada syndrome (bs) is an inherited ion channelopathy characterized by an electrocardiographic (ecg) pattern of a coved type st segment elevation in right precordial leads with or without right bundle branch block. case presentation: a 23-year old male presented with right lower quadrant abdominal pain. further evaluation revealed a diagnosis of acute appendicitis. the pa...

Correspondence to: Professor Keith A A Fox, Cardiovascular Research Unit, Centre for Cardiovascular Science, University of Edinburgh, Chancellor’s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK; [email protected] _________________________ A cute coronary syndrome (ACS) describes a spectrum of clinical conditions ranging from ST segment elevation myocardial infarction (MI) to non-S...