Genetic algorithm (GA) has become very popular for tackling computationally expensive numerical optimization problems. To optimize their performance and convergence rate, we propose demonstrate an embedded stage-specific gene expression framework (SGEF) with a two-tier coding scheme filter operator based on variational auto-encoder. For the first time, structure of auto-encoder is used to map p...

Purpose Indoleamine-2,3-dioxygenase (IDO) and Interleukin-6 (IL-6) contribute to poor therapeutic effects, tumor relapse and aggressive tumor growth. IDO and IL-6 incorporate a positive feedback signal loop to maintain IDO and IL-6 constitutive expression and facilitate tumor progression. Results IDO expression was associated with IL-6 expression and plasma IL-6 level (P<0.05). Concentrating ...