BACKGROUND Prosthetic implant infections caused by Staphylococcus aureus and epidermidis are major challenges for early diagnosis and treatment owing to biofilm formation on the implant surface. Extracellular DNA (eDNA) is actively excreted from bacterial cells in biofilms, contributing to biofilm stability, and may offer promise in the detection or treatment of such infections. QUESTIONS/PUR...

Acne is one of the most common skin pathologies; causes Propionibacterium acnes, an anaerobic and gram-positive microorganism that lives in hair follicles currently presents resistance to antibiotic-based treatments; this research topic has purpose evaluating antibiotic activity Cannabidiol oil against Staphylococcus aureus epidermidis level toxicity Artemia salina. For methodology, antibiogram...

Nigella sativa L. was allegedly to has antibacterial effect. The aim of this research is investigate effect ethanolic extracts 96% from Indonesia toward Staphylococcus aureus, Pseudomonas aeruginosa and Streptococcus epidermidis. Antibacterial activity L epidermidis using the well method. extract 12,5; 25;50 100% (mg/ml)inhibit growth aureus (with inhibition zone 11.06; 29.58; 28.22; 30.84 mm r...

An in vitro antimicrobial activity and phytochemical analysis of various extracts of Indigofera trita L. viz. petroleum ether, chloroform, acetone, ethanol and aqueous extracts were carried out. A total of 21 microorganisms (19 bacteria and 2 fungal strains) were used for antimicrobial activity by disc diffusion method and a standard procedure was used to identify the phytochemical constituents...

BACKGROUND People living with human immunodeficiency virus (PLWH) have been disproportionally affected by methicillin-resistant Staphylococcus aureus (MRSA) colonization and infection, in particular by clones USA300 and USA500. However, the contribution of epidemiological, bacterial, and immunological risk factors to the excess of S aureus in PLWH remain incompletely understood. METHODS In th...

Epidemiological data regarding catheter related blood stream infections (CRBI) in developing countries are scarce and essential to fabricate infection control and antibiotic prescription policies. Intravenous (IV) catheter tips and two synchronous blood samples from 297 patients with intravenous catheters and ≥ 48 hours stay were subjected to culture and sensitivity. Concurrent isolation of the...

Staphylococcus epidermidis is a harmless human skin colonizer responsible for ~20% of orthopedic device-related infections due to its capability to form biofilm. Nowadays there is an interest in the development of anti-biofilm molecules. Marine bacteria represent a still underexploited source of biodiversity able to synthesize a broad range of bioactive compounds, including anti-biofilm molecul...

Staphylococcus epidermidis is one of the most common causes of infections of prosthetic heart valves (prosthetic valve endocarditis [PVE]) and an increasingly common cause of infections of native heart valves (native valve endocarditis [NVE]). While S. epidermidis typically causes indolent infections of prosthetic devices, including prosthetic valves and intravascular catheters, S. epidermidis ...

OBJECTIVES Infectious endophthalmitis has occurred despite the use of antibiotics in irrigating solutions during implantation of intraocular lenses (IOLs). This infection is generally resistant to antibiotic therapy and, therefore, removal of the implant is necessary before eradication of the infection. This study was designed to assess the role of chosen dispersants and anti-adhesives in inhib...

Catheter-related bloodstream infections due to slow-growing Staphylococcus epidermidis small-colony variants (SCVs) are extremely difficult to treat. Daptomycin and vancomycin pharmacodynamics were evaluated against a site-directed hemB mutant of S. epidermidis displaying the SCV phenotype and compared to that of the parental strain. The maximal killing effect decreased by 7.7-fold for vancomyc...