Sharing genomic research data through controlled-access databases has increased in recent years. Policymakers and funding organizations endorse genomic data sharing in order to optimize the use of public funds and to increase the statistical power of databases. Well-established data access arrangements and data access committees (DACs)-responsible for reviewing and managing requests for access ...

New Challenges in Petascale Scientific Databases p. 1 Adventures in the Blogosphere p. 2 The Evolution of Vertical Database Architectures A Historical Review p. 3 Query Optimization in Scientific Databases Linked Bernoulli Synopses: Sampling along Foreign Keys p. 6 Query Planning for Searching Inter-dependent Deep-Web Databases p. 24 Summarizing Two-Dimensional Data with Skyline-Based Statistic...

The vast amount of gathered genomic data from Microarray and other high throughput experiments makes it extremely difficult for the researcher to interpret the data and form conclusions about the functions of the discovered genes. We can make use of extensive biomedical literature databases like Medline to find the functional similarity between genes using various information retrieval and clus...

We describe a general method for extending any pointer input device with an arbitrary set of commands. The proposed interface can be trained by the user to recognize certain cursor movement patterns and interpret them as special input events. Methods for extraction and recognition of such patterns are general enough to work with low-precision pointing devices, and they can be adjusted to provid...

Detection of protein families in large databases is one of the principal research objectives in structural and functional genomics. Protein family classification can significantly contribute to the delineation of functional diversity of homologous proteins, the prediction of function based on domain architecture or the presence of sequence motifs as well as comparative genomics, providing valua...

PURPOSE To estimate the burden of lifetime epilepsy (LTE) and active epilepsy (AE) and examine the influence of study characteristics on prevalence estimates. METHODS We searched online databases and identified articles using prespecified criteria. Random-effects meta-analyses were used to estimate the median prevalence in developed countries and in urban and rural settings in developing coun...

Score-based measures of molecular-sequence features provide versatile aids for the study of proteins and DNA. They are used by many sequence data base search programs, as well as for identifying distinctive properties of single sequences. For any such measure, it is important to know what can be expected to occur purely by chance. The statistical distribution of high-scoring segments has been d...

Recent suggestions that patients "hopelessly burned" be permitted to die peacefully have refocused attention on the accuracy of different methods of predicting whether an individual burn patient will survive. The purpose of this presentation is to compare the accuracy of mortality predictions based upon four different statistical methods: (1) Baux's rule which adds the patient's age in years to...

In the last decade research in Machine Learning has developed a variety of powerful tools for inductive learning and data analysis. On the other hand, research in International Relations has developed a variety of different conflict databases that are mostly analyzed with classical statistical methods. As these databases are in general of a symbolic nature, they provide an interesting domain fo...