نتایج جستجو برای: steatohepatitis

تعداد نتایج: 8373  

2014
Kira Bettermann Tabea Hohensee Johannes Haybaeck

Non-alcoholic fatty liver disease (NAFLD) which includes steatosis and steatohepatitis, in particular non-alcoholic steatohepatitis (NASH), is a rising health problem world-wide and should be separated from alcoholic steatohepatitis (ASH). NAFLD is regarded as hepatic manifestation of the metabolic syndrome (MetSy), being tightly linked to obesity and type 2 diabetes mellitus (T2DM). Developmen...

2017
Adryana Cordeiro Silvia Pereira Carlos José Saboya Andrea Ramalho

AIM To evaluate the relationship of nonalcoholic fatty liver disease (NAFLD) with nutritional status of vitamin D in extreme obesity. METHODS Descriptive cross-sectional study in individuals with class III obesity (BMI ≥ 40 kg/m2), aged ≥ 20 years to < 60 years. Data were obtained for weight, height, waist circumference (WC), and serum 25-hydroxyvitamin D (25(OH)D) levels. Vitamin D analysis ...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2006
Janardan K Reddy M Sambasiva Rao

Fatty liver disease (FLD), whether it is alcoholic FLD (AFLD) or nonalcoholic FLD (NAFLD), encompasses a morphological spectrum consisting of hepatic steatosis (fatty liver) and steatohepatitis. FLD has the inherent propensity to progress toward the development of cirrhosis and hepatocellular carcinoma. It is generally difficult to distinguish AFLD from NAFLD on morphological grounds alone desp...

2017
Mohamed M. Amin Rania F. Ahmed Dalia O. Saleh

Article history: Received on: 02/06/2017 Accepted on: 15/07/2017 Available online: 30/09/2017 Objective: The present study aimed to evaluate the neuro-protective and hepato-protective activity of melatonin (MLN) on non-alcoholic steatohepatitis (NASH) in albino rats induced by methionine and choline deficient (MCD) diet. Material and Methods: To achieve this aim, rats were fed MCD diet for 8 we...

2015
Petra Hirsova Gregory J. Gores

Nonalcoholic fatty liver disease (NAFLD) is becoming public health problem worldwide. A subset of patients develop an inflammatory disease, nonalcoholic steatohepatitis (NASH), characterized by steatosis, hepatocellular death, macrophage and neutrophil accumulation and varying stages of fibrosis. Hepatocyte cell death triggers the cellular inflammatory response and, therefore, reducing cell dea...

Journal: :Annals of hepatology 2011
Helma P Cotrim Edison R Parise Claudia P M S Oliveira Natalhie Leite Ana Martinelli João Galizzi Rita de Cássia Silva Angelo Mattos Leila Pereira Waldir Amorim Claúdia Ivantes Francisco Souza Marcelo Costa Lizomar Maia Mário Pessoa Frederico Oliveira

BACKGROUND The epidemiology and clinical characteristics of nonalcoholic fatty liver disease (NAFLD) in South America are not well known. Brazil is a largest country in this part of the world and the present study aimed to contribute with this information. METHODS This descriptive study included patients from medical centers around Brazil, who had diagnosis of NAFLD. They were selected from c...

Journal: :Journal of pediatric gastroenterology and nutrition 2000
Eve A Roberts

Non-alcoholic steatohepatitis (NASH) is an important liver disease in children; it can cause cirrhosis in children. The disease mechanism involves hepatic insulin resistance with hyperinsulinemia and changes in certain adipocytokines and inflammatory mediators. The differential diagnosis of childhood NASH includes metabolic disorders, drug hepatotoxicity, and alcoholic hepatitis in adolescent p...

2012
Said A. Al-Busafi Mamatha Bhat Philip Wong Peter Ghali Marc Deschenes

Nonalcoholic steatohepatitis (NASH) affects up to 3% of the North American population. It occurs as a manifestation of the insulin-resistant state and oxidative stress is thought to be a key component of its pathophysiology. Exercise and diet, which are the mainstay of therapy, are difficult to achieve and maintain with a disappointing long-term compliance record. There is growing literature on...

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