The CH(2)Cl(2)-MeOH (1:1) extract of the leaves of Hintonia standleyana and H. latiflora caused significant decrease in blood glucose levels in both normal and streptozotozin (STZ)-induced diabetic rats when compared with vehicle-treated groups (p < 0.05). These extracts were not toxic to mice according to the Lorke criteria. From the hypoglycemic extract of H. standleyana, two new 4-phenylcoum...

Blighiasapida is a plant belonging to the family of Sapindaceae. This study is aimed at evaluating the hypoglycemic and possible in vivo antioxidant activities of the aqueous extract of the stem bark of the plant for 21 days in alloxan-induced diabetic rats. Administration of the extract at 100mg/kg body weight significantly (P<0.05) decreased blood glucose levels, increased body weight as well...

In this study, forty-eight presumably healthy Wistar rats of both sexes weighing between 150160g were used. The animals were divided into two groups (N and D). Diabetes was induced with 65mg/kg body weight of streptozotocin intraperitoneally in group D animals. Diabetes was confirmed after 72 hours of induction using a glucometer. Anacardium occidentale Linn stembark was extracted using the met...

MAXIM. (Aceraceae) (Japanese name, Megusurino-ki) has been used as a folk medicine for the treatment of hepatic disorders and eye disease. The bark has been reported to contain various diarylheptanoid and phenolic compounds possessing several biological properties including hepatoprotective effects. In the course of our studies on the bioactive principles from natural sources, we have evaluated...

Background: Malaria is a worldwide threat, which affects millions of people. Although several antimalarial has been reported, they are either not effective or toxic. This study evaluated the antimalarial efficacy and safety of stem bark aqueous extracts of Khaya grandifoliola (KG) and Enantia chlorantha (EC) in Plasmodium berghie (NK65S) infected Swiss mice. Methods: Forty-two animals were gro...

The research was carried out to determine the effect of substitutional moringa stem bark extract (MB extract) with basil (BS on mortality, LC50 and LT50 Aedes aegypti larvae. design using completely randomized (CRD) consist 6 treatments including control (without MB BS extracts), 500 mg extract, 350 150 200 300 50 450 extract. Each treatment repeated 4 times. results variance analysis indicated...

BACKGROUND Albizzia Lebbeck Benth. is traditionally important plant and is reported to possess a variety of pharmacological actions. The present research exertion was undertaken to isolate and characterized the flavonoids from the extract of stem bark of Albizzia Lebbeck Benth. and to evaluate the efficacy of the isolated flavonoids on in-vitro models of type-II diabetes. Furthermore, the resul...

The growing problems of tuberculosis have led to the search for new anti-Mtb agents from higher plants. The stem bark of Spondias mombin was evaluated for its in vitro activity against Mycobacterium tuberculosis (H37Rv strain). Bioassay-guided fractionation of the methanol extract was carried out by Vacuum Liquid Chromatography (VLC) on Silica gel (230-400 mesh) and purification was done using ...

Objective: To evaluate antibacterial activity from four selected medicinal plants namely Mystroxylon aethiopicum, Lonchocarpus capassa, Albizia anthelmentica and Myrica salicifolia used for management of bacterial infection in Tanzania. Methods: Minimum Inhibitory Concentration (MIC) of plants extracts against the tested bacterial species was determined by using 96 wells microdilution method. I...

BACKGROUND There is wide spread interest in drugs derived from plants as green medicine is believed to be safe and dependable, compared with costly synthetic drugs that have adverse effects. METHODS We have attempted to evaluate the antioxidant, In vitro thrombolytic, antibacterial, antifungal and cytotoxic effects of Clausena heptaphylla (Rutaceae) stem bark extract ethanol extract. RESULT...