We have hypothesized that antiallergic activity of inhaled heparin is molecular weight dependent and mediated by "nonanticoagulant fractions" (NAF-heparin). Therefore, we studied comparative effects of high-, medium-, and ultralow-molecular-weight (HMW, MMW, and ULMW, respectively) NAF-heparins on acute bronchoconstrictor response (ABR) and airway hyperresponsiveness (AHR) in allergic sheep. Sp...

Abstract Background Hearing loss and cognitive impairment are postoperative complications which need more awareness by anaesthesiologists. We set out to investigate whether sevoflurane or propofol would have a negative impact on auditory function, attention, memory. This is prospective randomized controlled study was conducted patients who were candidates for elective laparoscopic cholecystecto...

Auditory brainstem response (ABR) and standard behavioral methods were compared by measuring in-air audiograms for an adult female harbor seal (Phoca vitulina). Behavioral audiograms were obtained using two techniques: the method of constant stimuli and the staircase method. Sensitivity was tested from 0.250 to 30 kHz. The seal showed good sensitivity from 6 to 12 kHz [best sensitivity 8.1 dB (...

Stem cell-based regenerative therapy is a potential cellular therapeutic strategy for patients with incurable brain diseases. Embryonic neural stem cells (NSCs) represent an attractive cell source in regenerative medicine strategies in the treatment of diseased brains. Here, we assess the capability of intracerebral embryonic NSCs transplantation for C57BL/6J mice with presbycusis in vivo. Morp...

BACKGROUND Nonbehavioral methods for identifying cisplatin ototoxicity are important for testing patients with cancer who become too tired or sick to provide a reliable response. The auditory brainstem response (ABR) is a nonbehavioral test that is sensitive to ototoxicity but can be time consuming to implement over a range of frequencies and/or levels. To address this issue, trains of stimuli ...

hyperbilirubinemia at neonatal period is one of the major deteriorating factors of the auditory system. if left untreated, it may cause certain cerebral damage. this study aims to evaluate the impact of hyperbilirubinemia on the hearing of neonate. this study was conducted on 35 newborn babies with jaundice (bilirubin more than 20 mg/dl). auditory brainstem response (abr) and transient evoked o...

INTRODUCTION Noonan syndrome (NS) is a heterogeneous genetic disease that affects many parts of the body. It was named after Dr. Jacqueline Anne Noonan, a paediatric cardiologist. CASE REPORT We report audiological tests and auditory brainstem response (ABR) findings in a 5-year old Malay boy with NS. Despite showing the marked signs of NS, the child could only produce a few meaningful words....

Test validity is determined by the proportion of results that are diagnostically confirmed and predicted on the measures used to identify the disease process. This article summarizes the results of a series of 224 stable high-risk infants who were screened by automated (ALGO-1) and conventional (Bio-logics LT) ABR instrumentation. Failure criteria was defined as the absence or prolongation of a...

OBJECTIVE Diabetes is the most common glucose level dependent metabolic disorder and studies have shown that hearing impairment can be a long-term subclinical complication. Studies to investigate auditory system involvement in diabetes has focused majorly on the auditory brainstem response (ABR), otoacoustic emission, and basic audiological measures. Hence in the current study, we used speech-e...

In this study, hydrogen production from starch wastewater using anaerobic sludge immobilized on maghemite nanoparticles (γ-Fe2O3) was investigated. Two anaerobic baffled reactors (ABR-1 and ABR-2) were operated at organic loading rate (OLR) of 3.63±0.43 g-COD/L.d and hydraulic retention time (HRT) of 10 h. The ABR-1 was inoculated with 3.5 g-VSS/L preheated sludge at 90°C for 30 minutes. The se...