BACKGROUND The optimal timing of surgical revascularization for patients presenting with ST-segment elevation myocardial infarction (STEMI) and impaired left ventricular function is not well established. This study aimed to examine the timing of surgical revascularization after STEMI in patients with ischemic heart disease and left ventricular dysfunction (LVD) by comparing early and late resul...

BACKGROUND Coronary artery disease (CAD) is a global problem with increasing incidence in Asia. Prior studies reported inter-ethnic differences in the prevalence of CAD rather than the severity of CAD. The angiographic "synergy between percutaneous coronary intervention (PCI) with taxus and cardiac surgery" (SYNTAX) score quantifies CAD severity and predicts outcomes. We studied CAD severity an...

BACKGROUND Clinical guidelines recommend similar medical therapy for patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation MI (NSTEMI). METHODS AND RESULTS Using the Get with the Guidelines-Coronary Artery Disease registry (GWTG-CAD), we analyzed data including 72 352 patients (48 966, NSTEMI; 23 386, STEMI) from 237 US sites between May 1, 2006 and Mar...

BACKGROUND Treatment times for ST-elevation myocardial infarction (STEMI) patients presenting to percutaneous coronary intervention hospitals have improved dramatically over the past 10 years, particularly for patients using emergency medical services. Limited data exist regarding treatment times and outcomes for patients who develop STEMI after hospital admission. METHODS AND RESULTS With th...

BACKGROUND Clinical predictors of high-risk STEMI patients may guide physicians to the type of treatment, as high-risk patients need more aggressive treatment than low-risk patients. There was no previous registry of STEMI patients in Thailand. OBJECTIVE To determine the clinical predictors of in-hospital mortality in STEMI patients from the Thai ACS MATERIAL AND METHOD: A multi-center prospe...

AIM The circulating RNA levels are predictive markers in several diseases. We determined the levels of circulating p53-related genes in patients with acute ST-segment elevation myocardial infarction (STEMI), indicating major heart muscle damage. METHODS Plasma RNA was extracted from the patients (n=45) upon their arrival to the hospital (STEMI 0h) and at four hours post-catheterization (STEMI...

Background Accurate diagnosis of ST elevation myocardial infarction (STEMI) is complicated by the presence of mimickers such as pericarditis, one of the most common reasons for (negative) emergency cardiac catheterization. Beyond common electrocardiogram (ECG) criteria for pericarditis, a rule of ST segment elevation in lead II greater than lead III (II > III), has been described in literatures...

Coronary artery disease (CAD) and ST-elevation myocardial infarction (STEMI) are predominantly diseases of middle-aged and older adults and when found in younger adults are usually associated with a strong family history. However, this report details the case of a nonobese 26-year-old Hispanic male who presented with an acute STEMI despite having no family history or other apparent risk factors...

The term “acute coronary syndrome” encompasses unstable angina and non-ST-segment elevation myocardial infarction (UA/ NSTEMI) and ST-segment elevation myocardial infarction (STEMI). UA/NSTEMI is the combination of two closely related clinical entities (i.e., a syndrome), whereas STEMI is a distinct clinical entity. UA/NSTEMI is characterized by an imbalance between myocardial oxygen supply and...

*Chair of 2004 Writing Committee; †Recused from voting on Section 8: Anticoagulants as Ancillary Therapy and Section 10: Anticoagulants; ‡Recused from voting on Section 5: Facilitated PCI; §Canadian Cardiovascular Society Representative; American Academy of Family Physicians Representative; ¶American College of Physicians Representative; **Recused from voting on Section 7: PCI After Fibrinolysi...