OBJECT Dose-volume data concerning the brainstem in stereotactic radiosurgery (SRS) for trigeminal neuralgia (TN) were analyzed in relation to associated complications. The authors present their set of data and compare it with currently cited information on brainstem dose tolerance associated with conventional fractionated radiation therapy and hypofractionated radiation treatment of other dise...

we present a rare case with history of neurological symptoms due to multiple brain metastases and no urological symptoms. during patient evaluation for primary tumor, transitional cell carcinoma (tcc) of left renal pelvis was found. the patient underwent gamma knife stereotactic radio-surgery for the metastatic brain lesions. radical nephroureterectomy was performed, and a 4-cycle course of pac...

Selecting optimal doses for radiosurgery requires a thorough consideration of existing dose-response data for radiation injury of brain and surrounding structures and of the doseresponse for the desired endpoint (tumor control, obliteration of a vascular malformation, relief of trigeminal neuralgia, etc.). This paper reviews the radiobiological and physics principles that should be considered i...

Initially designed for the treatment of functional brain targets, stereotactic radiosurgery (SRS) has achieved an important role in the management of a wide range of neurosurgical pathologies. The interest in the application of the technique for the treatment of pain, and psychiatric and movement disorders has returned in the beginning of the 1990s, stimulated by the advances in neuroimaging, c...

Stereotactic radiosurgery (SRS) involves the delivery of a very precise, focal dose of radiation to a target. Radiologic imaging is crucial for accurate delineation of the treatment volume in order to achieve maximal dose to the target and optimal sparing of the normal surrounding tissue. Conventional imaging refl ects only anatomic rather than functional properties of the tumor. In contrast, m...

3D Isodoselines innovation with Interior Optimization (IO) for prostate tumor BED model hyperfractionated Treatment Planning (TPO) application is further demonstrated. The implemented data was got additional-dual constrained evolutionary algorithm BED-LQ (Biological Effective Dose) in this cancer type. Results TPO IO-Graphical show a number of surfactal IO proven accuracy-feasibility the novelt...