Nephrotic syndrome is an unusual manifestation of IgA Nephropathy (IgAN). Some cases respond to steroid treatment. Here we describe a case-series of IgAN patients with steroid-responsive nephrotic syndrome. Twelve patients with IgAN with steroid-responsive nephrotic syndrome were evaluated and followed up. All patients presented with generalized edema. Renal insufficiency was found in two patie...

INTRODUCTION. Childhood idiopathic nephrotic syndrome is characterized by frequent relapsing courses or steroid dependency. Levamisole is a popular drug for treatment of these patients. The purpose of this study was to evaluate levamisole in children with steroid-dependent nephrotic syndrome. MATERIALS AND METHODS. We retrospectively studied 304 children with a diagnosis of steroid-dependent ne...

BACKGROUND Keloids are a common problem with significant recurrence rates despite intralesional steroid treatment and multimodal therapy. OBJECTIVE The purpose of this study was to evaluate the efficacy of using a 5-fluorouracil (5-FU)/steroid mixture to treat keloids over the past 7 years, comparing the results with use of steroid treatment alone. METHODS Patient charts from 1999 to 2006 w...

Six male strength athletes, three illicit anabolic steroid users and three non-steroid users were monitored over several months as they underwent normal training and competition routines. Subjects completed the Profile of Mood States (POMS) questionnaire, Buss-Durke Hostility Inventory and the Rosenweig Picture Frustration Test on four occasions: two on-drug periods and two off-drug periods for...

Framingham Heart Study suggests that dysfunction of steroid receptor coactivator-1 may be involved in the development of hypertension. However, there is no functional evidence linking steroid receptor coactivator-1 to the regulation of blood pressure. We used immunohistochemistry to map the expression of steroid receptor coactivator-1 protein in mouse brain, especially in regions implicated in ...

■ EVIDENCE-BASED ANSWER Subacromial steroid injection may provide a small, short-term benefit compared with placebo. The short-term effectiveness of steroid injection compared with nonsteroidal anti-inflammatory agents (NSAIDs) remains unclear. Steroid injections are better than physiotherapy alone in the short term. However, injection does not appear to provide any meaningful longterm benefit ...

Steroid hormones act in specific regions of the brain to alter behavior and physiology. While it has been well established that the bioavailability of the steroid and the expression of its receptor is critical to understanding steroid action in brain, the importance of nuclear receptor coactivators in brain is becoming more apparent. This review will focus on the function of the p160 family of ...

Pemfigus vulgaris (PV) adalah penyakit autoimun vesikobulosa pada kulit dan membran mukosa yang secara histologi ditandai bula intraepidermal disebabkan oleh akantolisis. Steroid sistemik merupakan terapi utama PV. Artikel ini membahas efek samping steroid parenteral pemfigus vulgaris.
 Pemphigus Vulgaris is an autoimmune blistering disease of skin and mucous membranes, histologically defi...