The annular ligament provides a compliant connection of the stapes to the oval window. To estimate the stiffness characteristics of the annular ligament, human temporal bone measurements were conducted. A force was applied sequentially at several points on the stapes footplate leading to different patterns of displacement with different amounts of translational and rotational components. The sp...

Oncogenes deregulate fundamental cellular functions, which can lead to development of tumors, tumor-cell invasion, and metastasis. As the mechanical properties of cells govern cell motility, we hypothesized that oncogenes promote cell invasion by inducing cytoskeletal changes that increase cellular stiffness. We show that the oncogenes simian virus 40 large T antigen, c-Myc, and cyclin E induce...

BACKGROUND The cornea is responsible for two-thirds of the eye's refractive power which is a function of the shape and refractive index. The aim of this present study is to examine human eyes in vivo for corneal shape changes in response to short-term elevation in intraocular pressure. METHODS Videokeratographic and tonometric assessments at baseline were compared with the same assessments wh...

Fiber networks are assemblies of one-dimensional elements representative of materials with fibrous microstructures such as collagen networks and synthetic nonwovens. The mechanics of random fiber networks has been the focus of numerous studies. However, fiber crimp has been explicitly represented only in few cases. In the present work, the mechanics of cross-linked networks with crimped atherma...

A mechanical model is proposed which quantitatively describes the dynamics of the centre of gravity (c.g.) during the take-off phase of the long jump. The model entails a minimal but necessary number of components: a linear leg spring with the ability of lengthening to describe the active peak of the force time curve and a distal mass coupled with nonlinear visco-elastic elements to describe th...

A system identification problem is investigated for high-rise buildings to identify the story stiffnesses of a shear-bending model (SB model). In the previously proposed stiffness identification method due to the present authors, the shear and bending stiffnesses of the SB model were identified by means of the subspace and inverse-mode methods. The lowest mode of horizontal displacements and fl...

Steel Plate Shear Wall (SPSW) is made from thin steel plate which in turn are framed by the beams and columns of structural system. In recent year they are proved to be very effective and economical for resisting lateral loads such as earthquake and wind loads.The present work targets to study the behaviour of single frame SPSW with different plate thicknesses, rigid and non-rigid frame members...