Working in the context of symmetric spectra, we describe and study a homotopy completion tower for algebras and left modules over operads in the category of modules over a commutative ring spectrum (e.g., structured ring spectra). We prove a strong convergence theorem that for 0-connected algebras and modules over a (−1)-connected operad, the homotopy completion tower interpolates (in a strong ...

This article aims to redefine the concept of Thirdspace and make a trilateral relationship between the three concepts of real space, virtual space and the user. To do so, not only the concept of Thirdspace has to be redefined, but also a new understanding of virtual space as a relatively independent space is required. This three-sided relation requires a new understanding of the relationship be...

We study the connection between the Goodwillie tower of the identity and the lower central series of the loop group on connected spaces. We define the simplicial theory of homotopy n-nilpotent groups. This notion interpolates between infinite loop spaces and loop spaces. We prove, that the set-valued algebraic theory obtained by applying π0 is the theory of ordinary n-nilpotent groups and that ...

The procedure followed by the Nuclear Metrology Laboratory (LMN), at the Nuclear and Energy Research Institute (IPEN), for the primary standardization of (177)Lu is described. This radionuclide is widely used in radiopharmacy due to its convenient half-life and emitted beta ray energies. The (177)Lu solution was supplied during an international comparison sponsored by BIPM in 2009 and the prima...

We study the connection between the Goodwillie tower of the identity and the lower central series of the loop group on connected spaces. We define the simplicial theory of homotopy n-nilpotent groups. This notion interpolates between infinite loop spaces and loop spaces. We prove that the set-valued algebraic theory obtained by applying π0 is the theory of ordinary n-nilpotent groups and that t...

Nuclear migration is a critical component of many cellular and developmental processes. The nuclear envelope forms a barrier between the cytoplasm, where mechanical forces are generated, and the nucleoskeleton. The LINC complex consists of KASH proteins in the outer nuclear membrane and SUN proteins in the inner nuclear membrane that bridge the nuclear envelope. How forces are transferred from ...

OBJECTIVE To assess the correlation between the anorectal function and bladder detrusor function in patients with complete spinal cord injury (SCI) according to the type of lesion. METHODS Medical records of twenty-eight patients with SCI were included in this study. We compared the anorectal manometric and urodynamic (UD) parameters in total subjects. We analyzed the anorectal manometric and...

Mutations in Parkin gene are responsible of 50% of cases with autosomal recessive juvenile-onset Parkinson’s disease (ARJP). Although 21 parkin alternative splice variants have been cloned so far, most of the studies have focused their attention on the full-length protein. Despite the expression of the originally cloned protein has been observed in human blood cells, there is currently no study...

Caenorhabditis elegans has a single lamin gene, designated lmn-1 (previously termed CeLam-1). Antibodies raised against the lmn-1 product (Ce-lamin) detected a 64-kDa nuclear envelope protein. Ce-lamin was detected in the nuclear periphery of all cells except sperm and was found in the nuclear interior in embryonic cells and in a fraction of adult cells. Reductions in the amount of Ce-lamin pro...

Acute laminitis is an inflammatory disease of the equine foot that often occurs secondarily to sepsis or systemic inflammation associated with gastrointestinal disease. It has been suggested that laminitis is similar to multiple organ dysfunction syndrome in humans, although in horses the weight-bearing laminar epithelium of the foot appears to be the tissue most sensitive to insult and the fir...