This in vivo experimental study evaluated the efficacy of fluoride-releasing elastomers in the control of Streptococcus mutans levels in the oral cavity. Forty orthodontic patients were recruited and divided into two groups of 20. Fluoride-releasing elastomeric ligature ties (Fluor-I-Ties, Ortho Arch Co. Inc., USA) were used in the experimental group, and conventional elastomeric ligature ties ...

Long-term spaceflights will eventually become an inevitable occurrence. Previous studies have indicated that oral infectious diseases, including dental caries, were more prevalent in astronauts due to the effect of microgravity. However, the impact of the space environment, especially the microgravity environment, on the virulence factors of Streptococcus mutans, a major caries-associated bacte...

Phytochemical screening, antioxidant and antibacterial activities of aqueous and methanolic crude extracts of Commiphora kerstingii leaves were investigated. The antioxidant and antibacterial properties of different solvent extracts of Commiphora kerstingii plant were scrutinized. The phytochemical screening of the various extracts was carried out using standard methods and the results revealed...

Objectives: This study aimed to assess the antimicrobial effects of aloe vera hydroalcoholic extract and 0.2% chlorhexidine (CHX) mouthwash on Streptococcus sanguinis (S. sanguinis), Streptococcus salivarius (S. salivarius) and Streptococcus mutans (S. mutans) in vitro. Materials and Methods: Four concentrations (25%, 50%, 75% and 100%) of hydroalcoholic extract of aloe vera were prepared. S. ...

The Streptococcus mutans serotype c gtfA gene encodes a 55-kilodalton sucrose-hydrolyzing enzyme. Analysis of S. mutans gtfA mutants revealed that the mutant strains were specifically impaired in the ability to use melibiose as a sole carbon source. S. mutans gtfA mutant strains synthesized less alpha-galactosidase activity inducible by raffinose than wild-type strains. Melibiose (an inducer in...

Twenty-four mutacin-producing Streptococcus mutans strains were screened for their propensity to produce class II one-peptide bacteriocin using a deferred antagonism assay. Streptococcus salivarius and 3 mutants defective in their mannose phosphotransferase systems (mannose-PTS) were used as sensitive strains to identify which mannose-PTS could act as the docking site for class II one-peptide b...

Dental caries is an infectious disease that caused by the interaction between host, diet, and a diverse microbial community. This study illustrated anticariogenic effects of THYJ-15 against Streptococcus mutans, major agent dental caries. was identified as Latilactobacillus sakei subsp. through 16S rRNA sequencing, with similarity 99.72% to L. JCM 1157T. The cell-free supernatant observed MIC v...

BACKGROUND & OBJECTIVES The mutans streptococci (MS) are a group of 7 species of dental cariesassociated bacteria of which Streptococcus mutans and Streptococcus sobrinus are the most important in humans. Many MS produce bacteriocin-like inhibitory substances (BLIS), some of which have been characterised as small peptides capable of inhibiting the growth of closely-related species. These peptid...

Biofilms are polymicrobial, with diverse bacterial species competing for limited space and nutrients. Under healthy conditions, the different species in biofilms maintain an ecological balance. This balance can be disturbed by environmental factors and interspecies interactions. These perturbations can enable dominant growth of certain species, leading to disease. To model clinically relevant i...