OBJECTIVES To explore the relation between ill health after the Gulf war and vaccines received before or during the conflict. To test the hypothesis that such ill health is limited to military personnel who received multiple vaccines during deployment and that pesticide use modifies any effect. DESIGN Cross sectional study of Gulf war veterans followed for six to eight years after deployment....

A study was made of post-traumatic stress disorder in 200 children aged 7-11 years who had witnessed a public hanging next to their school in Isfahan, Islamic Republic of Iran. A standard checklist was completed through interviews with the children's parents 3 months after the event. Post-traumatic stress disorder symptoms were identified in 104 children (52%), with 88 suffering re-experiences,...

The serotonergic system has been found to play a crucial role in the development of affective disorders, and more recently a functional polymorphism in the serotonin transporter gene, the 5-HTTLPR has been found to be associated with different manifestations of depressive illness. Stress has also been implicated in the background of these disorders. Research increasingly implicates that the s a...

We report artifactual degradation of pharmaceutical compounds containing primary and secondary amines during peroxy radical-mediated oxidative stress carried out using azoalkane initiators. Two degradation products were detected when model drug compounds dissolved in methanol/water were heated to 40°C with radical initiators such as 2,2'-azobis(2-methylpropionitrile) (AIBN). The primary artifac...

The purpose of this study was to clarify the psychological factors of bus drivers' instability that were related to bus passengers' accidents according to the hypothesis model based on the stress concept of Lazarus and Folkman (1984). This research was carried out in 2006. Participants of the study were 39 Japanese male bus drivers. Their average age was 40.2 (SD: 11.1). The average duration of...

BACKGROUND Medical school is recognized as a stressful environment that often has a negative effect on students' academic performance, physical health, and psychosocial well-being. Previous studies have not identified differences between depressed and nondepressed and anxious and nonanxious medical students' experiences of stress or their reactions to stressors. The present study aimed to ident...

early life stress during fetal development has been hypothesized to predispose several neurological and psychiatric disorders in adulthood. the purpose of this study was to investigate the effect of maternal stress on the volume of granular cells, total number of dark neurons and also the distribution of glycol-conjugates and changes of terminal sugars in the dentate gyrus. pregnant sprague-daw...

BACKGROUND Circulating microRNAs (miRNAs/miRs) are regulated in patients with coronary artery disease. The impact of transient coronary ischemia on circulating miRNA levels is unknown. We aimed to investigate circulating miRNA kinetics in response to cardiac stress in patients with or without significant coronary stenosis. METHODS AND RESULTS Eighty of 105 screened patients with stable corona...

Subcritical crack growth in fused silica is treated as a stress assisted chemical reaction between water and strained bonds at the crack tip. In this work, the kinetics of the reaction is modeled by assuming the stress reduces the energy barrier of the activated complex by affecting both the activation enthalpy and entropy, where the stress dependence can take different forms. This theory is co...

Atopic dermatitis leads to, and can be triggered by, stress. Psychological interventions have been shown to have positive effects on skin status, itch and scratching behaviour. However, it has not been analysed whether stress management leads to a change in physiological stress level and psychophysiological stress reaction under acute stress in this patient group. In this study 28 patients with...