OBJECTIVES Patients without voluntary finger extension early post-stroke are suggested to have a poor prognosis for regaining upper limb capacity at 6 months. Despite this poor prognosis, a number of patients do regain upper limb capacity. We aimed to determine the time window for return of voluntary finger extension during motor recovery and identify clinical characteristics of patients who, d...

Objectives: ncluding stroke. The aim of this study was to systematically review the clinical evidence CT for stroke.Methods: To identify randomized controlled trials (RCTs) reporting effectiveness and/or safety CT, seven databases including PubMed, EMBASE, and Cochrane Library were searched articles published from January 2000 February 2021 without language restrictions. Meta-analysis performed...

BACKGROUND AND PURPOSE Surface neuromuscular electrical stimulation (sNMES) after stroke aims to improve upper limb function and reduce shoulder pain, but current evidence of effectiveness is inconclusive. We have undertaken a randomized controlled trial to evaluate sNMES to the shoulder after acute stroke. METHODS One hundred seventy-six patients, within 10 days of stroke onset, were randomi...

Hemiplegic cerebral palsied (CP) children account 30% of CP children1, characterized by affected arm and leg on one side of the body2. Hemiplegic children had difficulties in performing fine motor hand activities and had abnormal upper limb posturing during gait and in any activities required effort3. Combination of spasticity, weakness, and sensory and motor control deficits reduced functional...

Quantification of rehabilitation progress is necessary for accurately assessing clinical treatments. A three-dimension (3D) upper extremity (UE) kinematic model was developed to obtain joint angles of the trunk, shoulder and elbow using a Vicon motion analysis system. Strict evaluation confirmed the system's accuracy and precision. As an example of application, the model was used to evaluate th...

Aberrant vestibular nuclear function is proposed to be a principle driver of limb muscle spasticity after stroke. We sought to determine whether altered cortical modulation of descending vestibulospinal pathways post-stroke could impact the excitability of biceps brachii motoneurons. Twelve chronic hemispheric stroke survivors aged 46-68 years were enrolled. Sound evoked biceps myogenic potenti...

In patients who have had a stroke, is a set of botulinum toxin A (BTA) injections more effective than placebo in improving wrist and finger spasticity? D e s i g n Randomized (unclear allocation conceal-ment*), blinded (clinicians, patients, and outcome assessors),* placebo-controlled trial with 12-week follow-up (Botox Post-Stroke Spasticity Study Group). 126 patients who were ≥ 21 years of ag...

The authors evaluated the long-term efficacy and safety of botulinum toxin type A (BTX-A) in poststroke spasticity patients who completed a 12-week placebo-controlled study and received multiple open-label treatments with 200 to 240 U BTX-A for 42 weeks. Significant and sustained improvements were observed for Disability Assessment and Ashworth scores. Adverse events were generally mild. This e...