نتایج جستجو برای: stromal tumors
تعداد نتایج: 211664 فیلتر نتایج به سال:
Octamer-binding transcription factor 4 (OCT-4) is an important marker of cellular de-differentiation that can be induced by environmental stressors, such as acidity. Here we demonstrate that chronic acidic stress in solid tumors induced OCT-4 expression in fibroblasts and other stromal cells in four tumor models. The results have implications for how tumors utilize pH modulation to recruit asso...
Received October 2009 Accepted November 2009 INTRODUCTION A gastrointestinal stromal tumor (GIST) is primarily located in the gastrointestinal tract. It is classified as a mesenchymal tumor that shows a CD117 (c-KIT)-positive mesenchymal spindle or epithelioid neoplasm. Tumors outside the gastrointestinal tract that were histologically similar to GISTs and showed immunopositivity for CD117 were...
Gastrointestinal stromal tumors (GISTs) represent the majority of primary non-epithelial neoplasms of the digestive tract, most frequently expressing the KIT protein detected by immunohistochemical staining for the CD117 antigen. Extragastrointestinal stromal tumors (EGISTs), neoplasms with immunohistological features overlapping those of GISTs, are found in the abdomen outside of the gastroint...
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