A full length cDNA (1463 bp) encoding isocitrate lyase (EC 4.1.3.1) of Strongyloides stercoralis is described. The nucleotide sequence of this insert identified a cDNA coding for the isocitrate lyase. The conceptually translated amino acid sequence of the open reading frame for S. stercoralis isocitrate lyase encodes a 450 amino acid residue protein with an apparent molecular weight of 50 kDa a...

We present a case of Strongyloides stercoralis hyperinfection syndrome in the frame of a Good syndrome. The Good Syndrome is a rare cause of combined Band T-cell immunodeficiency that occurs in association with a thymoma. Patients affected with Good syndrome have increased susceptibility to infections.

background: strongyloides stercoralis , the etiological agent of strongyloidiasis, is one of the most common parasitic nema­tode with the unique ability to complete its life cycle and proliferate within the host. although it is an endemic parasite in iran, no molecular characterization is available on isolates originated from the country. therefore, this study was con­ducted for molecular ident...

Accurate diagnosis of infection with the parasite Strongyloides stercoralis is hampered by the low concentration of larvae in stool, rendering parasitological diagnosis insensitive. Even if the more sensitive agar plate culture method is used repeated stool sampling is necessary to achieve satisfactory sensitivity. In this manuscript we describe the development of a coproantigen ELISA for diagn...

Strongyloidiasis is a parasitic neglected disease caused by the nematode Strongyloides stercoralis affecting 30 to 100 million people worldwide. Complications, strongly associated with alcoholism, organ transplants, and HTLV-1 virus, often arise due to late diagnosis, frequently leading to patient death. Lack of preemptive diagnosis is not the only difficulty when dealing with this parasite, si...

Because diagnosis of strongyloidiasis by stool examination is unreliable and because of the potential for serious disease in Strongyloides infections, there is need for improved diagnostic aids to facilitate recognition and treatment of this parasitic infection. Serologic testing, when available, requires antigen preparation from infected primates or dogs that can be difficult to maintain. Seve...

With an increase in travel and an influx of immigrants and refugees from the tropics over the last few decades, clinicians in Rhode Island are more commonly encountering tropical diseases. The Federation for American Immigration Reform estimated that the average annual rate of increase in the foreign-born population in Rhode Island to be 2400 persons, with the Dominican Republic and Guatemala t...

Infections with Strongyloides stercoralis and other helminths represent important, yet often neglected issues in developing countries. Indeed, strongyloidiasis can be fatal, but only a few studies provide information regarding its health relevance in Africa. S. stercoralis is an intestinal nematode that can persist in the human host for decades after the initial infection and can progress to fu...

More sensitive diagnostic methods for detecting worms’ eggs are needed in areas with low soil-transmitted helminth (STH) prevalence. The Harada-Mori technique was first introduced by Mr. Harada and Mori. This is easy, simple, does not require sophisticated equipment. based on larvae tropism nature the water to concentrate of hookworms Strongyloides stercoralis. Since its application 1955, this ...

BACKGROUND Investigate the role of latent strongyloidiasis infection in patients at the University Hospital, Honduras. METHODS Prospective observational cohort study during 20 non consecutive months from March 2009 to February 2011. Epidemiological and clinical data obtained from patients excreting Strongyloides stercoralis larvae in stool who consulted at the hospital were recorded and analy...