Array-based comparative genomics hybridization (aCGH) has gained prevalence as an effective technique for measuring structural variations in the genome. Copy-number variations (CNVs) form a large source of genomic structural variation, but it is not known whether phenotypic differences between intra-species groups, such as divergent human populations, or breeds of a domestic animal, can be attr...

Studies of families and twins show the importance of genetic factors affecting susceptibility to bipolar disorder and suggest substantial genetic and phenotypic complexity. Robust and replicable genome-wide significant associations have recently been reported in genome-wide association studies at several common polymorphisms, including variants within the genes CACNA1C, ODZ4, and NCAN. Strong e...

The calculation of the load carrying capacity of variable thickness circular plates subjected to arbitrary rotational symmetric loading is presented. The analysis considers plate materials that obey either the square or the Tresca yield criterion. By using upper and lower bound theorems of limit analysis, corresponding estimations for the load carrying capacity of the plate are obtained. It is ...

Mangroves migrate northward in Florida and colonize marshes historically dominated by salt marsh species. In theory, this migration should be facilitated by greater numbers of propagules stemming from increased reproductive activity and greater genetic variability caused by outcrossing. We aimed to determine if stand reproduction and % outcrossing were affected by cold stress (stress increases ...

Previous studies of Veronica and related genera were weakly supported by molecular and paraphyletic taxa. Here, we report the complete chloroplast genome sequence of Veronica nakaiana and the related species Veronica persica and Veronicastrum sibiricum. The chloroplast genome length of V. nakaiana, V. persica, and V. sibiricum ranged from 150,198 bp to 152,930 bp. A total of 112 genes comprisin...

Background. Quantifying the interfraction dose variations in the organs at risk (OAR) in HDR intracavitary brachytherapy (HDR ICBT). Methods. Rectum and bladder were contoured in 44 patients of cervical carcinoma on CT after each fraction of HDR ICBT (9 Gy/2 fractions). Interfraction dose variations (VARact) were calculated. Rigid image registration of consecutive fraction images allowed quanti...

Introduction: Estimates of the global inventory of water on Mars based on a determination of the amount of water required to erode the outflow channels suggest that a quantity equivalent to a global ocean 0.5 to 1 km deep may be stored in the planet’s subsurface [1, 2]. As this inventory post dates the timing of the most efficient processes that may have lead to its removal, the majority of thi...

QuikSCAT backscatter is generally higher over urban areas than surrounding vegetated areas. Azimuthal anisotropy has been observed over some urban areas, but the strength of the azimuthal anisotropy in the urban backscatter signal has not been well quantified. This study investigates radar azimuthal anisotropy in urban areas. QuikSCAT L1B σ observations are compared for urban, non-urban, and un...

Bunocephalus is the most species-rich Aspredinidae genus, corresponding to a monophyletic clade with 13 valid species. However, many species have their classification put in question. Here, we analyzed individuals from four Amazonian populations of Bunocephalus coracoideus by cytogenetic and molecular procedures. The geographic distribution, genetic distances and karyotype data indicate that ea...

Facular emission is one of the major contributors to long-term solar irradiance variations. Reconstructions of past facular variations, however, are strongly hampered by the lack of reliable proxies, particularly on time-scales longer than a solar cycle. We consider the five potential facular proxies with records covering more than 40 years. By suitably weighting and combining them we create a ...