By describing 3 clinical cases of unusual testicular non germinal tumors, including an adenoma of the rete testis, an undifferenciated sex cord tumor and a mesothelioma of the tunica vaginalis, we make a literature review of the unusual testicular tumors and testicular apendix, including their incidence and management. Also and as one of our conclusions, we expose the importance of the intraope...

Crossed testicular ectopia (CTE) is generally defined as both testes located in the same hemiscrotum and contralateral hydrocele with the absence of a testis. However, the initial presentation of CTE in an infant as an incarcerated inguinal hernia is extremely rare. We report on a 10-month-old infant with CTE, who visited the emergency room presenting with a left incarcerated inguinal hernia. A...

Background: Busulfan is a chemotherapy drug that is widely used for cancer treatment. However, administration of busulfan to male patients with malignant diseases may cause temporary or permanent sterility. Therefore, research into drugs or Materials to reduce the side effects of busulfan on the male reproductive system is necessary. In the present study the protective effects of L-carnitine an...

  SUMMARY With the aim of surgical epidemiology nature of undescended testis, we examined 8034 school age boys in the city of Tehran. We invatted affected persons to Loghman-e-Hakim Medical Center for repeated examination and further diagnostic in­vestigations, results are: Among 8034 persons 82 had undescended testis, it means 1 .02 % , 56 % are in the right, and 33%  in the left, 11 % are...

Background: Male infertility is responsible for approximately 50% of infertility in the world. Reactive oxygen species (ROS) is one of the causative agents of infertility in males which effects on sperm quality and function. In this study, the effects of oxidative stress induced by tertiary-butyl hydroperoxide (TBHP) were investigated on sperm quality, testis tissue and miRNAs expression. Mater...

Background: Nitric oxide (NO) is an important molecular regulator in biology of reproductive systems. In addition, critical level of NO is essential for Implantation and embryo’s development. However, increased levels of NO can have a wide range of adverse effects. This molecule is synthesized from L-Arginine (L.A) by Nitric oxide Synthetase (NOS) activity. In the current study, the effects of ...

background breast cancer is the most common malignancy in women around the world so finding new biomarkers for early detection and also study on molecular aspects of breast cancer is valuable. cancer testis genes are a group of genes expressed solely in testis and in a range of human malignancies. objectives in this study we determined the expression of cancer testis genes tsga10, tex101 and od...

objective: the goals of the study are evaluation the effect(s) of food deprivation as a social stress on testis structure. we also investigated the effects of melatonin treatment as an antioxidant component and inequality on the effect(s) of food deprivation. methods: we investigated the improving effects of melatonin and social stress (food deprivation) on 42 male rats in 7 groups including co...

PURPOSE Testicular microlithiasis (TM) is a relatively rare clinical entity of controversial significance characterized by the existence of hydroxyapatite microliths located in the seminiferous tubules. The aim of this study was to observe the natural course of changes in the calcific density of pediatric TM. MATERIALS AND METHODS We included a total of 23 TM patients undergoing scrotal ultra...

Introduction: We present a retrospective 2-year follow-up cohort of 103 men with testicular microlithiasis (TML) and discuss patient compliance and the value of surveillance. Methods: A retrospective analysis of patients examined with scrotal ultrasonography (US) in the period from 2008 through 2010 was performed. A total of 103 men with TML were diagnosed and offered US follow-up every 6 month...