A surface molecularly imprinted nanowire is designed by chemical polymerization of dopamine in neutral aqueous solution, which shows high binding capacity and acceptable specific recognition behavior towards template proteins.

COVID-19 caused by a SARS-CoV-2 infection was first reported from Wuhan, China, and later recognized as pandemic on March 11, 2020, the World Health Organization (WHO). Gold standard nucleic acid molecular-based testing have largely satisfied requirements of early diagnosis management this infectious disease; however, these techniques are expensive not readily available for point-of-care (POC) ...

This paper presents novel handheld analyzer with disposable lab-on-chips for electrical detection of anesthetic propofol in human serum samples for clinical diagnostics. The developed on-chip biosensors are based on molecularly imprinted conducting polymer techniques. In this paper, we have designed, fabricated, and characterized the developed system with disposable lab-on-chips for detection o...

Recently, microcantilever-based technology has emerged as a viable sensing platform due to its many advantages such as small size, high sensitivity, and low cost. However, microcantilevers lack the inherent ability to selectively identify hazardous chemicals (e.g., explosives, chemical warfare agents). The key to overcoming this challenge is to functionalize the top surface of the microcantilev...

An important challenge for scientific research is the production of artificial systems able to mimic the recognition mechanisms occurring at the molecular level in living systems. A valid contribution in this direction resulted from the development of molecular imprinting. By means of this technology, selective molecular recognition sites are introduced in a polymer, thus conferring it bio-mime...

Abstract Egg allergy is one of the most common allergies in humans. Allergenic egg protein as ovalbumin abundant found white. A selective electrode electrochemical analysis for albumin from white was developed based on magnetic molecularly imprinted polymers (albumin-MMIPs) modified a screen-printed electrode. Surface modification applied using methyl methacrylate polymer to create surface spec...

Advancement in molecularly imprinted biomimetics has aided developing robust artificial recognition-based materials, which can be customized for bio/chemo-sensing of distinct molecules. The present study reports a simple one-step synthesis and analysis protein-imprinted polymer thin films as recognition element directly onto solid support. Dopamine been explored versatile functional monomer (MI...

A single bi-functional monomer, N,O-bismethacryloyl ethanolamine (NOBE), was used in precipitation polymerization system to synthesize molecularly imprinted polymer (MIP) microspheres. Highly specific binding sites were obtained for N-terminal protected neuropeptides, Boc-Leu-enkephalin and Pyr-Leu-enkephalin. The use of NOBE allowed binding sites to be formed in polymer microspheres that are a...

An interdigitated electrode sensor was designed and microfabricated for measuring the changes in the capacitance of three phosphate selective molecularly imprinted polymer (MIP) formulations, in order to provide hydroponics users with a portable nutrient sensing tool. The MIPs investigated were synthesised using different combinations of the functional monomers methacrylic acid (MAA) and N-ally...

Decreased blood level of high-density lipoprotein (HDL) is one of the essential criteria in diagnosing metabolic syndrome associated with the development of atherosclerosis and coronary heart disease. Herein, we report the synthesis of a molecularly imprinted polymer (MIP) that selectively binds HDL, namely, HDL-MIP, and thus serves as an artificial, biomimetic sensor layer. The optimized polym...