Background: Pre-eclampsia is a multifactorial pregnancy specific vascular disorder characterized by hypertension and proteinuria. It affects around 3-5% pregnancies worldwide. The aetiology and pathophysiology of PE remain poorly understood. But it is generally accepted defective placentation during the early stage of pregnancy most likely in combination with maternal and environmental factors ...

We introduce a future orientation index to quantify the degree to which Internet users worldwide seek more information about years in the future than years in the past. We analyse Google logs and find a striking correlation between the country's GDP and the predisposition of its inhabitants to look forward.

We have recently developed a data-mining pipeline that comprehensively identifies cancer unique susceptibilities, following the concept of Synthetic Lethality (SL). The approach enables, for the first time, to identify and harness genome-scale SL-networks to accurately predict gene essentiality, drug response, and clinical prognosis in cancer.

Dynamical four-point susceptibilities measure the extent of spatial correlations in the dynamics of glass forming systems. We show how these susceptibilities depend on the lengthscales that necessarily form part of their definition. The behavior of these susceptibilities is estimated by means of an analysis in terms of renewal processes within the context of dynamic facilitation. The analytic r...

One hundred four isolates of Campylobacter jejuni from poultry in Alberta, Canada, collected during 2001 were tested for resistance to 10 antimicrobial agents using agar dilution. This study provides a baseline of resistance profiles and the mechanisms of resistance observed in C. jejuni in poultry from Alberta, Canada.

We present an asymptotically exact solution of a local copper-oxide model abstracted from the multi-band models. The phase diagram is obtained through the renormalization-group analysis of the partition function. In the strong coupling regime, we find an exactly solved line, which crosses the quantum critical point of the mixed valence regime separating two different Fermi-liquid (FL) phases. A...

Expectations about the shape of statistical interactions play a crucial role in the study of differential susceptibility and other types of person-environment interplay. These expectations shape methodological guidelines and inform the interpretation of empirical findings; however, their logic has never been explicitly examined. This study is the first systematic exploration of the evolution of...

This study tested the diathesis-stress component of Beck's (1967) cognitive theory of depression. Initially, participants completed measures assessing cognitive organization of the self-schema and depressive symptoms. One year later, participants completed measures assessing cognitive organization of the self-schema, depressive symptoms, and negative life events. Hierarchical multiple regressio...