The aim of this study was to investigate the histopathological changes in zebrafish larvae following embryonic exposure to nanoparticles of magnesium oxide (MgONPs). The toxicity of metal oxide nanoparticles is attracting increasing attention. Among these nanomaterials, MgONPs are particularly interesting as a low cost and environmentally-friendly material. Histological investigations are used ...

Multiple Sclerosis (MS) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. In this study for evaluation effect of mercuric on progression of MS we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model of MS in C57BL/6 mi...

The release of metformin, a drug used in the treatment cancer and diabetes, from poly(2-hydroxyethyl methacrylate), pHEMA, hydrogel-based microneedle patches is demonstrated vitro. Tuning composition pHEMA hydrogels enables preparation robust with mechanical properties such that they would penetrate skin (insertion force single to be ≈40 N). Swelling experiments conducted at 20, 35, 60 °C show ...

fresh semen obtained from infertile men occasionally exhibits the total absence of motile sperm (100%asthenozoospermia). vitality tests may reveal that a proportion of the immotile sperm has functional membranes, which are considered viable. an easy test for the prior determination of sperm viability may assist in sperm selection for the microinjection of oocytes. the main objective of this stu...

the objective of the present study is to develop and investigate the swelling behavior of ph-sensitive superporous hydrogel (sph) and sph composite (sphc). a novel superporous hydrogel containing poly (methacrylic acid-co-acrylamide) was synthesized from methacrylic acid and acrylamide through the aqueous solution polymerization, using n,n-methylenebisacrylamide as a crosslinker and ammonium pe...

semen analysis, sperm dna fragmentation (sdf) and hypo-osmotic swelling test (host) are usually performed for the evaluation of sperm fertilizing ability. there are some debates over the necessity of sdf and host incorporation in male infertility work-up.semen of 77 men was evaluated by sdf and host through three semen analyses. sperm parameters were arranged into different categories: < 5%, 5-...

the transport properties of liquids and gases through polymeric materialsplay a very important role in some areas of industrial applications. in thisstudy, natural rubber (nr)/caco3 composites were prepared by melt mixingmethod. by equilibrium swelling test, the transport process of toluene in the prepared natural rubber composites was investigated. the diffusion and transport of toluene throug...