Twenty-seven types of commercial tampons from five manufacturers were tested in a sealed-syringe method to determine their effect on the growth of Staphylococcus aureus and the production of toxic shock syndrome toxin 1. In this improvement of the syringe method, the available air is limited to that which is contained within the sealed syringe containing the tampon. The culture medium was buffe...

The increasing use of human growth hormone (hGH) treatment has resulted in the introduction of a number of alternative delivery systems to conventional syringe and needle administration. We examined patients' evaluation of a new delivery system, the Kabipen (Kabi-Vitrum). We also assessed the accuracy of hGH delivery by the Kabipen. Of the 77 survey respondents 13 had used only the Kabipen, 14 ...

This study examined the use of ultrasonication to improve the injectability of an aqueous calcium phosphate paste. Ultrasonication was applied to the paste through the plunger of the delivery syringe. A factorial design of experiments with three investigated factors, liquid to powder ratio (LPR) (38%, 39% and 40%), the size of the delivery syringe (5 and 10 ml) and the amplitude of the 20 kHz p...

Background and objectives: Hawthorn as an ethno-pharmaceutical plant has been consumed for 2,500 years. Flowers, leaves and fruits of hawthorn are rich in antioxidant and polyphenols and are popular in the treatment of congestive heart failure. Methods: In the present study, by using various media and plant hormones the regeneration and callogenesis capacity of...

Sir,?With reference to the query on p. 297 of your May issue, the method used by me for sterilizing syringes Js described below:? I carry a few " Soloid " examethylenetetrainine (B. W. & Co.) and a spoon in my injection outfit. The needle !s boiled in the spoon over the burning soloid which gives out a good heat. The boiling water is also drawn into the syringe several times. I have given a goo...

www.ondrugdelivery.com 27 In this article, Mahesh Chaubal, PhD, Senior Director, Drug Development, R&D Medical Products, Baxter Healthcare Corporation, provides a glimpse of some of the challenges faced during the development of viscous formulations of biopharmaceutical products for injection, from a formulator’s perspective, especially when the finished product is filled in a prefilled syringe...

BACKGROUND Coverage is used as one indicator of needle and syringe program (NSP) effectiveness. At the individual level, coverage is typically defined as an estimate of the proportion of a person who injects drugs' (PWID) injecting episodes that utilise a sterile syringe. In this paper, we explore levels of individual syringe coverage and its changes over time. METHODS Data were extracted fro...

Immunocontraceptive vaccines have shown some promise for fertility control of white-tailed deer (Odocoileus virginianus) in urban and suburban habitats where traditional methods of population control may not be applicable. Currently, the only contraceptive vaccine approved by the U.S. Environmental Protection Agency for use in white-tailed deer is GonaConTM Immunocontraceptive Vaccine, but it i...

OBJECTIVE The purpose of this prospective, randomized, blinded study was to compare the pain of injection and post-injection pain of the AMSA injection using the computer-assisted Wand Plus injection system versus a conventional syringe. STUDY DESIGN Using a crossover design, 40 subjects randomly received 2 blinded AMSA injections using the Wand Plus system and a conventional syringe, at 2 se...