ROPIVACAINE is an amide local anesthetic with a long duration of action that was developed because of the high risk of cardiac complications induced by bupivacaine. Preclinical studies have confirmed its reduced systemic and cardiac toxicity as compared with bupivacaine, and clinical studies have also been very reassuring regarding the risk of ropivacaine-induced systemic toxicity. There have, ...

Chloroquine is frequently used to treat systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). With long term treatment, associated toxicity is well known, with retinopathy been the most common complication. Other chronic complications include skin disorders (hyperpigmentation), blood dyscrasias, corneal deposits, encephalopathy, neuropathy, myopathy, and impairment of audito...

Diabetes mellitus is a systemic disease that involves multiple organs.several documented studies indicated that  prevalence of gallstone in diabetics is higher than  nondiabetics.thus,rate of acute cholecystitis and cholecystectomy should be higher in these patients.some studies have showen that the risk of postoperative complications is higher in the diabetics.this cross-sectional study has be...

The lupus anticoagulant was found in the plasma of 31 of 60 patients with systemic lupus erythematosus and other connective tissue disorders (mixed connective tissue disease, systemic vasculitis, polyarteritis nodosa, primary sicca syndrome, discoid lupus, Behcet's syndrome, and systemic sclerosis). Strong associations were found with biological false positive seroreaction for syphilis and thro...

background: optimal timing and mode of treatment for patients with coarctation of the aorta ( coa ) remain controversial, particularly in children. surgery, balloon dilatation, and stent implantation have all proven effective in the treatment of moderate or severe obstruction. the aim of this study was to investigate the complications of coa stenting angioplasty in pediatric patients. methods: ...

Over the last few decades, the incidence of invasive candidal infections in neonatal intensive care units has increased dramatically. Various complications, such as arthritis, endocarditis, meningitis, and endophthalmitis, have been reviewed. We present the case of a premature infant with systemic candidemia. Arthritis was discovered 6 months after completion of amphotericin B therapy, and was ...

OBJECTIVE The proportion of patients with systemic lupus erythematosus (SLE) who manifest retinal involvement increases many fold in patients with active systemic disease. The objective of this report is to stress upon the significance of comprehensive ophthalmic assessment of all SLE patients to prevent and manage blinding ocular manifestations of the disease. METHODS Retrospective case revi...

A utosomal dominant polycystic kidney disease (ADPKD) is a genetic condition characterised by the formation of multiple fluid-filled renal cysts and kidney enlargement. Potential complications of ADPKD include adult-onset end-stage kidney disease, early-onset hypertension and nephrolithiasis. ADPKD is also associated with systemic conditions including intracranial cerebral aneurysm and polycyst...

Paraquat poisoning is associated with very high mortality and often results in severe complications including pulmonary fibrosis and multi-organ failure. Majorities of the reported cases had paraquat exposure from oral route either due to accidental intake or suicidal attempt. Systemic complications from dermal exposure were infrequently reported. We reported a patient suffering from acute rena...

Computed tomography-guided percutaneous transthoracic fine-needle aspiration biopsy of lung lesions is a well known diagnostic technique. Nevertheless, it has some complications; such as pneumothorax, intraparenchymal hemorrhage and hemoptysis, which are not rare. Air embolism is one of the rare but potentially fetal complications of this procedure. Herein, we report the case of a 69-year-old m...